Methylcymantrene | CAS#12108-13-3 | Gasoline antiknock additive.

MedKoo Cat#: 592347 | Name: Methylcymantrene

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methylcymantrene is a Gasoline antiknock additive.

Chemical Structure

Methylcymantrene

CAS#12108-13-3

Theoretical Analysis

MedKoo Cat#: 592347

Name: Methylcymantrene

CAS#: 12108-13-3

Chemical Formula: C9H7MnO3

Exact Mass: 217.9776

Molecular Weight: 218.09

Elemental Analysis: C, 49.57; H, 3.24; Mn, 25.19; O, 22.01

Price and Availability

Size	Price	Availability	Quantity
1g	USD 250.00	Back order

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Related CAS #

No Data

Synonym

Methylcymantrene; Antiknock-33

IUPAC/Chemical Name

Manganese, tricarbonyl((1,2,3,4,5-eta)-1-methyl-2,4-cyclopentadien-1-yl)-

InChi Key

KPKMQYCSOVZNMI-UHFFFAOYSA-N

InChi Code

CC[0:-]C=CC=C@1.O[+]#C[-].O[+]#C[-].O[+]#C[-].Mn[+]

SMILES Code

C[C-]1C=CC=C1.[O+]#[C-].[O+]#[C-].[O+]#[C-].[Mn+]

Appearance

Liquid

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Methylcymantrene is a Gasoline antiknock additive.

In vitro activity:

The conjugation of cymantrene CpMn(CO)(3) to cell-penetrating peptide hCT(18-32)-k7 alters the intracellular distribution in MCF-7 cells compared to the unmodified peptide, as visualized by fluorescence microscopy, and leads to an increased nuclear accumulation; the peptide and cymantrene compound themselves are not toxic, but the bioconjugate shows a significant cytotoxicity with an IC(50) value of 36 micromol l(-1). Reference: Chem Commun (Camb). 2008 Nov 21;(43):5604-6. https://pubmed.ncbi.nlm.nih.gov/18997966/

In vivo activity:

TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 218.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

Neundorf I, Hoyer J, Splith K, Rennert R, Peindy N'dongo HW, Schatzschneider U. Cymantrene conjugation modulates the intracellular distribution and induces high cytotoxicity of a cell-penetrating peptide. Chem Commun (Camb). 2008 Nov 21;(43):5604-6. doi: 10.1039/b812799a. Epub 2008 Sep 26. PMID: 18997966.

In vitro protocol:

In vivo protocol:

TBD