PYX 1 | CAS#140842-17-7 | orexigenic peptide

MedKoo Cat#: 598060 | Name: PYX 1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PYX 1 is a potent orexigenic peptide.

Chemical Structure

PYX 1

CAS#140842-17-7

Theoretical Analysis

MedKoo Cat#: 598060

Name: PYX 1

CAS#: 140842-17-7

Chemical Formula: C70H105Cl2N19O16

Exact Mass: 1537.7364

Molecular Weight: 1539.62

Elemental Analysis: C, 54.61; H, 6.87; Cl, 4.61; N, 17.29; O, 16.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

PYX 1; PYX-1; PYX1; Ac-Tyr-3-(Cl2Bzl)-ile-asn-leu-ile-D-thr-arg-gln-arg-tyr-NH2;

IUPAC/Chemical Name

(S)-2-((2S,5R,8S,11S,14S,17S,20S)-14-(2-amino-2-oxoethyl)-8,17-di((S)-sec-butyl)-20-(3-(2,6-dichlorobenzyl)-4-hydroxybenzyl)-2-(3-guanidinopropyl)-5-((S)-1-hydroxyethyl)-11-isobutyl-4,7,10,13,16,19,22-heptaoxo-3,6,9,12,15,18,21-heptaazatricosanamido)-N1-((S)-1-(((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)pentanediamide

InChi Key

LNUMCIVYAIEPPL-XFBIFGDYSA-N

InChi Code

InChI=1S/C70H105Cl2N19O16/c1-9-35(5)56(89-65(104)51(82-38(8)93)31-40-20-24-53(95)41(29-40)32-43-44(71)14-11-15-45(43)72)66(105)88-52(33-55(74)97)63(102)87-50(28-34(3)4)64(103)90-57(36(6)10-2)67(106)91-58(37(7)92)68(107)85-47(17-13-27-81-70(78)79)60(99)84-48(23-25-54(73)96)62(101)83-46(16-12-26-80-69(76)77)61(100)86-49(59(75)98)30-39-18-21-42(94)22-19-39/h11,14-15,18-22,24,29,34-37,46-52,56-58,92,94-95H,9-10,12-13,16-17,23,25-28,30-33H2,1-8H3,(H2,73,96)(H2,74,97)(H2,75,98)(H,82,93)(H,83,101)(H,84,99)(H,85,107)(H,86,100)(H,87,102)(H,88,105)(H,89,104)(H,90,103)(H,91,106)(H4,76,77,80)(H4,78,79,81)/t35-,36-,37-,46-,47-,48-,49-,50-,51-,52-,56-,57-,58+/m0/s1

SMILES Code

CC[C@@H]([C@H](NC([C@@H](NC(C)=O)Cc1cc(Cc2c(Cl)cccc2Cl)c(O)cc1)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)Cc3ccc(O)cc3)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)[C@@H](O)C)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(N)=O)=O)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,539.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lee MC, Lawson DC, Pappas TN. Neuropeptide Y functions as a physiologic regulator of cephalic phase acid secretion. Regul Pept. 1994 Aug 4;52(3):227-34. PubMed PMID: 7800854. 2: Oellerich WF, Malik KU. Neuropeptide Y modulates the vascular response to periarterial nerve stimulation primarily by a postjunctional action in the isolated perfused rat kidney. J Pharmacol Exp Ther. 1993 Sep;266(3):1321-9. PubMed PMID: 8371140. 3: Ault DT, Radeff JM, Werling LL. Modulation of [3H]Dopamine release from rat nucleus accumbens by neuropeptide Y may involve a sigma1-like receptor. J Pharmacol Exp Ther. 1998 Feb;284(2):553-60. PubMed PMID: 9454797.