Bam 1745 | CAS#133136-47-7 | adrenomedullary secretory vesicle

MedKoo Cat#: 598029 | Name: Bam 1745

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bam 1745 is a significant component of adrenomedullary secretory vesicles; fragment of chromogranin B Gln(580)-Tyr(593).

Chemical Structure

Bam 1745

CAS#133136-47-7

Theoretical Analysis

MedKoo Cat#: 598029

Name: Bam 1745

CAS#: 133136-47-7

Chemical Formula: C79H116N20O25

Exact Mass: 1744.8420

Molecular Weight: 1745.91

Elemental Analysis: C, 54.35; H, 6.70; N, 16.05; O, 22.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Bam 1745; Bam-1745; Bam1745; Pyroglutamyl peptide bam-1745;

IUPAC/Chemical Name

(2S,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S)-5-((1H-imidazol-4-yl)methyl)-14-(3-amino-3-oxopropyl)-23-(2-carboxyethyl)-17-(carboxymethyl)-32-(3-guanidinopropyl)-2-(4-hydroxybenzyl)-35-((S)-3-(4-hydroxyphenyl)-2-((S)-5-oxopyrrolidine-2-carboxamido)propanamido)-8,11,20-triisobutyl-29-isopropyl-26-methyl-4,7,10,13,16,19,22,25,28,31,34-undecaoxo-3,6,9,12,15,18,21,24,27,30,33-undecaazaheptatriacontanedioic acid

InChi Key

JHRLXGDAMQJZGK-ARICVWHCSA-N

InChi Code

InChI=1S/C79H116N20O25/c1-37(2)27-51(70(115)93-53(29-39(5)6)71(116)95-55(32-44-35-83-36-85-44)74(119)98-58(78(123)124)31-43-14-18-46(101)19-15-43)91-67(112)49(20-23-59(80)102)90-76(121)57(34-63(108)109)96-72(117)52(28-38(3)4)92-68(113)50(22-25-61(104)105)88-65(110)41(9)86-77(122)64(40(7)8)99-69(114)47(11-10-26-84-79(81)82)89-75(120)56(33-62(106)107)97-73(118)54(30-42-12-16-45(100)17-13-42)94-66(111)48-21-24-60(103)87-48/h12-19,35-41,47-58,64,100-101H,10-11,20-34H2,1-9H3,(H2,80,102)(H,83,85)(H,86,122)(H,87,103)(H,88,110)(H,89,120)(H,90,121)(H,91,112)(H,92,113)(H,93,115)(H,94,111)(H,95,116)(H,96,117)(H,97,118)(H,98,119)(H,99,114)(H,104,105)(H,106,107)(H,108,109)(H,123,124)(H4,81,82,84)/t41-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,64-/m0/s1

SMILES Code

OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC([C@H](CC2=CNC=N2)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CC(O)=O)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](CC4)NC4=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,745.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Flanagan T, Taylor L, Poulter L, Viveros OH, Diliberto EJ Jr. A novel 1745-dalton pyroglutamyl peptide derived from chromogranin B is in the bovine adrenomedullary chromaffin vesicle. Cell Mol Neurobiol. 1990 Dec;10(4):507-23. PubMed PMID: 1982622. 2: Dillen L, Boel S, De Potter WP, Claeys M. Mass spectrometric characterization of bovine chromaffin granule peptides related to chromogranin B. Biochim Biophys Acta. 1992 Mar 27;1120(1):105-12. PubMed PMID: 1554736.