Synonym
Diazoluminolmelanin; DALM;
IUPAC/Chemical Name
5-amino-2,3-dihydrophthalazine-1,4-dione (S)-2-amino-3-(3-amino-4-hydroxyphenyl)propanoate
InChi Key
RJGOMFVTRMUHDP-FJXQXJEOSA-N
InChi Code
InChI=1S/C9H12N2O3.C8H7N3O2/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14;9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3,7,12H,4,10-11H2,(H,13,14);1-3,10-11H,9H2/t7-;/m0./s1
SMILES Code
O=C([C@H](Cc1cc(N)c(O)cc1)N)O.Nc2cccc(c([nH][nH]3)=O)c2c3=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
373.36
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Kiel JL, Alls JL, Mason PA, Erwin DN. Luminescent radio frequency radiation dosimetry. Bioelectromagnetics. 1999;Suppl 4:46-51. PubMed PMID: 10334714.
2: Kiel JL, O'Brien GJ, Dillon J, Wright JR. Diazoluminomelanin: a synthetic luminescent biopolymer. Free Radic Res Commun. 1990;8(2):115-21. PubMed PMID: 2318420.
3: Bruno JG, Parker JE, Holwitt E, Alls JL, Kiel JL. Preliminary electrochemiluminescence studies of metal ion-bacterial diazoluminomelanin (DALM) interactions. J Biolumin Chemilumin. 1998 May-Jun;13(3):117-23. PubMed PMID: 9693978.
4: Bruno JG, Kiel JL. Luminol and diazoluminomelanin as indicators of HL-60 cell differentiation. In Vitro Cell Dev Biol Anim. 1993 Sep;29A(9):737-41. PubMed PMID: 8407717.
5: Bruno JG, Kiel JL. Synthesis of diazoluminomelanin (DALM) in HL-60 cells for possible use as a cellular-level microwave dosimeter. Bioelectromagnetics. 1994;15(4):315-28. PubMed PMID: 7980660.
6: Kiel JL, Seaman RL, Mathur SP, Parker JE, Wright JR, Alls JL, Morales PJ. Pulsed microwave induced light, sound, and electrical discharge enhanced by a biopolymer. Bioelectromagnetics. 1999;20(4):216-23. PubMed PMID: 10230935.