MedKoo Cat#: 598001 | Name: N-Valyltryptophan

Description:

WARNING: This product is for research use only, not for human or veterinary use.

N-Valyltryptophan is a dipeptide composed of valine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.

Chemical Structure

N-Valyltryptophan
N-Valyltryptophan
CAS#24587-37-9

Theoretical Analysis

MedKoo Cat#: 598001

Name: N-Valyltryptophan

CAS#: 24587-37-9

Chemical Formula: C16H21N3O3

Exact Mass: 303.1583

Molecular Weight: 303.36

Elemental Analysis: C, 63.35; H, 6.98; N, 13.85; O, 15.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
N-Valyltryptophan; Val-trp; L-Valyl-L-tryptophan;
IUPAC/Chemical Name
L-valyl-L-tryptophan
InChi Key
LZDNBBYBDGBADK-KBPBESRZSA-N
InChi Code
InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1
SMILES Code
O=C(O)[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](C(C)C)N)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 303.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li Y, Wang F, Zhang PZ, Yang M. [Chemical Constituents from Periplaneta americana]. Zhong Yao Cai. 2015 Oct;38(10):2038-41. Chinese. PubMed PMID: 27254913. 2: Lunow D, Kaiser S, Rückriemen J, Pohl C, Henle T. Tryptophan-containing dipeptides are C-domain selective inhibitors of angiotensin converting enzyme. Food Chem. 2015 Jan 1;166:596-602. doi: 10.1016/j.foodchem.2014.06.059. Epub 2014 Jun 18. PubMed PMID: 25053098. 3: Boudesocque L, Kapel R, Paris C, Dhulster P, Marc I, Renault JH. Concentration and selective fractionation of an antihypertensive peptide from an alfalfa white proteins hydrolysate by mixed ion-exchange centrifugal partition chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 15;905:23-30. doi: 10.1016/j.jchromb.2012.07.034. Epub 2012 Aug 3. PubMed PMID: 22939269. 4: Hatanaka A, Miyahara H, Suzuki KI, Sato S. Isolation and identification of antihypertensive peptides from antarctic krill tail meat hydrolysate. J Food Sci. 2009 May-Jul;74(4):H116-20. doi: 10.1111/j.1750-3841.2009.01138.x. PubMed PMID: 19490329. 5: Holden HM, Matthews BW. The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis. J Biol Chem. 1988 Mar 5;263(7):3256-60. PubMed PMID: 3343246.