MedKoo Cat#: 597997 | Name: Aviglycine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aviglycine is an antibiotic.

Chemical Structure

Aviglycine
Aviglycine
CAS#49669-74-1

Theoretical Analysis

MedKoo Cat#: 597997

Name: Aviglycine

CAS#: 49669-74-1

Chemical Formula: C6H12N2O3

Exact Mass: 160.0848

Molecular Weight: 160.17

Elemental Analysis: C, 44.99; H, 7.55; N, 17.49; O, 29.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Aviglycine; NSC 234613; NSC-234613; NSC234613; Antibiotic Ro 20-4468/001; Ro 4468;
IUPAC/Chemical Name
(S,E)-2-amino-4-(2-aminoethoxy)but-3-enoic acid
InChi Key
USGUVNUTPWXWBA-JRIXXDKMSA-N
InChi Code
InChI=1S/C6H12N2O3/c7-2-4-11-3-1-5(8)6(9)10/h1,3,5H,2,4,7-8H2,(H,9,10)/b3-1+/t5-/m0/s1
SMILES Code
O=C(O)[C@@H](N)/C=C/OCCN
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 160.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jin JK, Adams DO, Ko Y, Yu CW, Lin CH. Aviglycine and propargylglycine inhibit conidial germination and mycelial growth of Fusarium oxysporumf. sp. luffae. Mycopathologia. 2004 Oct;158(3):369-75. PubMed PMID: 15645176. 2: Cottrell TE, Wood BW, Ni X. Application of plant growth regulators mitigates chlorotic foliar injury by the black pecan aphid (Hemiptera: Aphididae). Pest Manag Sci. 2010 Nov;66(11):1236-42. doi: 10.1002/ps.2000. PubMed PMID: 20715019. 3: Asimakopoulou A, Panopoulos P, Chasapis CT, Coletta C, Zhou Z, Cirino G, Giannis A, Szabo C, Spyroulias GA, Papapetropoulos A. Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE). Br J Pharmacol. 2013 Jun;169(4):922-32. doi: 10.1111/bph.12171. PubMed PMID: 23488457; PubMed Central PMCID: PMC3687671. 4: Zhu C, Yang N, Guo Z, Qian M, Gan L. An ethylene and ROS-dependent pathway is involved in low ammonium-induced root hair elongation in Arabidopsis seedlings. Plant Physiol Biochem. 2016 Aug;105:37-44. doi: 10.1016/j.plaphy.2016.04.002. Epub 2016 Apr 2. PubMed PMID: 27074220. 5: Niimi H, Watanabe M, Serizawa H, Koba T, Nakamura I, Mii M. Amiprophosmethyl-induced efficient in vitro production of polyploids in raphanobrassica with the aid of aminoethoxyvinylglycine (AVG) in the culture medium. Breed Sci. 2015 Dec;65(5):396-402. doi: 10.1270/jsbbs.65.396. Epub 2015 Dec 1. PubMed PMID: 26719742; PubMed Central PMCID: PMC4671700. 6: Zhang J, Yu G, Wen W, Ma X, Xu B, Huang B. Functional characterization and hormonal regulation of the PHEOPHYTINASE gene LpPPH controlling leaf senescence in perennial ryegrass. J Exp Bot. 2016 Feb;67(3):935-45. doi: 10.1093/jxb/erv509. Epub 2015 Dec 6. PubMed PMID: 26643195; PubMed Central PMCID: PMC4737083. 7: Shi Y, Tian S, Hou L, Huang X, Zhang X, Guo H, Yang S. Ethylene signaling negatively regulates freezing tolerance by repressing expression of CBF and type-A ARR genes in Arabidopsis. Plant Cell. 2012 Jun;24(6):2578-95. doi: 10.1105/tpc.112.098640. Epub 2012 Jun 15. PubMed PMID: 22706288; PubMed Central PMCID: PMC3406918. 8: Karaman S, Ozturk B, Aksit H, Erdogdu T. The effects of pre-harvest application of aminoethoxyvinylglycine on the bioactive compounds and fruit quality of 'Fortune' plum variety during cold storage. Food Sci Technol Int. 2013 Dec;19(6):567-76. doi: 10.1177/1082013212457668. Epub 2013 Feb 4. PubMed PMID: 23382556. 9: Iqbal N, Trivellini A, Masood A, Ferrante A, Khan NA. Current understanding on ethylene signaling in plants: the influence of nutrient availability. Plant Physiol Biochem. 2013 Dec;73:128-38. doi: 10.1016/j.plaphy.2013.09.011. Epub 2013 Sep 20. Review. PubMed PMID: 24095919. 10: Liu S, Gao H, Wu X, Fang Q, Chen L, Zhao FJ, Huang CF. Isolation and Characterization of an Aluminum-resistant Mutant in Rice. Rice (N Y). 2016 Dec;9(1):60. doi: 10.1186/s12284-016-0132-3. Epub 2016 Nov 11. PubMed PMID: 27837430; PubMed Central PMCID: PMC5106411. 11: Völz R, Heydlauff J, Ripper D, von Lyncker L, Groß-Hardt R. Ethylene signaling is required for synergid degeneration and the establishment of a pollen tube block. Dev Cell. 2013 May 13;25(3):310-6. doi: 10.1016/j.devcel.2013.04.001. PubMed PMID: 23673332. 12: Böttcher C, Burbidge CA, Boss PK, Davies C. Interactions between ethylene and auxin are crucial to the control of grape (Vitis vinifera L.) berry ripening. BMC Plant Biol. 2013 Dec 23;13:222. doi: 10.1186/1471-2229-13-222. PubMed PMID: 24364881; PubMed Central PMCID: PMC3878033. 13: Son SH, Chang SC, Park CH, Kim SK. Ethylene negatively regulates EXPA5 expression in Arabidopsis thaliana. Physiol Plant. 2012 Mar;144(3):254-62. doi: 10.1111/j.1399-3054.2011.01552.x. Epub 2012 Jan 3. PubMed PMID: 22145846. 14: Chae SC, Kim HH, Park SU. Ethylene inhibitors enhance shoot organogenesis of gloxinia (Sinningia speciosa). ScientificWorldJournal. 2012;2012:859381. doi: 10.1100/2012/859381. Epub 2012 Oct 17. PubMed PMID: 23125558; PubMed Central PMCID: PMC3483669. 15: Jespersen D, Huang B. Proteins associated with heat-induced leaf senescence in creeping bentgrass as affected by foliar application of nitrogen, cytokinins, and an ethylene inhibitor. Proteomics. 2015 Feb;15(4):798-812. doi: 10.1002/pmic.201400393. PubMed PMID: 25407697. 16: Takahashi-Asami M, Shichijo C, Tsurumi S, Hashimoto T. Ethylene Is Not Responsible for Phytochrome-Mediated Apical Hook Exaggeration in Tomato. Front Plant Sci. 2016 Nov 23;7:1756. eCollection 2016. PubMed PMID: 27933077; PubMed Central PMCID: PMC5120132. 17: Jespersen D, Yu J, Huang B. Metabolite responses to exogenous application of nitrogen, cytokinin, and ethylene inhibitors in relation to heat-induced senescence in creeping bentgrass. PLoS One. 2015 Mar 30;10(3):e0123744. doi: 10.1371/journal.pone.0123744. eCollection 2015. PubMed PMID: 25822363; PubMed Central PMCID: PMC4379107. 18: Camacho-Cristóbal JJ, Martín-Rejano EM, Herrera-Rodríguez MB, Navarro-Gochicoa MT, Rexach J, González-Fontes A. Boron deficiency inhibits root cell elongation via an ethylene/auxin/ROS-dependent pathway in Arabidopsis seedlings. J Exp Bot. 2015 Jul;66(13):3831-40. doi: 10.1093/jxb/erv186. Epub 2015 Apr 28. PubMed PMID: 25922480; PubMed Central PMCID: PMC4473985. 19: Lewis DR, Negi S, Sukumar P, Muday GK. Ethylene inhibits lateral root development, increases IAA transport and expression of PIN3 and PIN7 auxin efflux carriers. Development. 2011 Aug;138(16):3485-95. doi: 10.1242/dev.065102. Epub 2011 Jul 19. PubMed PMID: 21771812. 20: Li G, Song H, Li B, Kronzucker HJ, Shi W. Auxin Resistant1 and PIN-FORMED2 Protect Lateral Root Formation in Arabidopsis under Iron Stress. Plant Physiol. 2015 Dec;169(4):2608-23. doi: 10.1104/pp.15.00904. Epub 2015 Oct 14. PubMed PMID: 26468517; PubMed Central PMCID: PMC4677891.