MedKoo Cat#: 592273 | Name: Arsenazo I

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Arsenazo I is a calcium-sensitive, metallochromic dye used as reagent.

Chemical Structure

Arsenazo I
CAS#520-10-5

Theoretical Analysis

MedKoo Cat#: 592273

Name: Arsenazo I

CAS#: 520-10-5

Chemical Formula: C16H13AsN2O11S2

Exact Mass: 547.9177

Molecular Weight: 548.33

Elemental Analysis: C, 35.05; H, 2.39; As, 13.66; N, 5.11; O, 32.10; S, 11.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Arsenazo I; AI3-52540; AI3 52540; AI352540
IUPAC/Chemical Name
2,7-Naphthalenedisulfonic acid, 3-((2-arsonophenyl)azo)-4,5-dihydroxy-
InChi Key
NJZWLEZSGOTSHR-VHEBQXMUSA-N
InChi Code
InChI=1S/C16H13AsN2O11S2/c20-12-7-9(31(25,26)27)5-8-6-13(32(28,29)30)15(16(21)14(8)12)19-18-11-4-2-1-3-10(11)17(22,23)24/h1-7,20-21H,(H2,22,23,24)(H,25,26,27)(H,28,29,30)/b19-18+
SMILES Code
O=S(C1=C(/N=N/C2=CC=CC=C2[As](O)(O)=O)C(O)=C3C(O)=CC(S(=O)(O)=O)=CC3=C1)(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 548.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rochat S, Severin K. Pattern-based sensing with metal-dye complexes: sensor arrays versus dynamic combinatorial libraries. J Comb Chem. 2010 Jul 12;12(4):595-9. doi: 10.1021/cc1000727. PubMed PMID: 20518552. 2: Zaubitzer F, Riis-Johannessen T, Severin K. Sensing of peptide hormones with dynamic combinatorial libraries of metal-dye complexes: the advantage of time-resolved measurements. Org Biomol Chem. 2009 Nov 21;7(22):4598-603. doi: 10.1039/b912400d. Epub 2009 Sep 3. PubMed PMID: 19865694. 3: Dubenska L, Levytska H, Poperechna N. Polarographic investigation of reduction process of some azodyes and their complexes with rare earths. Talanta. 2001 Apr 12;54(2):221-31. PubMed PMID: 18968244. 4: Migdalski J, Błaz T, Zrałka B, Lewenstam A. Galvanic cell without liquid junction for potentiometric determination of copper. Anal Chim Acta. 2007 Jul 2;594(2):204-10. Epub 2007 May 21. PubMed PMID: 17586116. 5: Li SW, Li N, Zhao FL, Li KA. [Study on determination of protein with Arsenazo I using resonance light scattering technique]. Guang Pu Xue Yu Guang Pu Fen Xi. 2002 Aug;22(4):619-22. Chinese. PubMed PMID: 12938380. 6: Salama G, Scarpa A. Magnesium permeability of sarcoplasmic reticulum. Mg2+ is not countertransported during ATP-dependent Ca2+ uptake by sarcoplasmic reticulum. J Biol Chem. 1985 Sep 25;260(21):11697-705. PubMed PMID: 3930482. 7: Baylor SM, Chandler WK, Marshall MW. Optical measurements of intracellular pH and magnesium in frog skeletal muscle fibres. J Physiol. 1982 Oct;331:105-37. PubMed PMID: 6984069; PubMed Central PMCID: PMC1197744. 8: Dorogi PL, Santarius U, Neumann E. Arsenazo I and tetramethylmurexide as optical calcium indicators. Anal Biochem. 1982 Jul 15;124(1):27-36. PubMed PMID: 7125225. 9: Celon E, Degetto S, Marangoni G, Baracco L. Rapid determination of milligram amounts of uranium in organic complexes with pyridine-2,6-dicarboxylic acid as titrant and arzenazo I as indicator after oxygen-flask combustion. Talanta. 1979 Feb;26(2):160-2. PubMed PMID: 18962403. 10: Williamson J, Scott-Finnigan TJ. Trypanocidal activity of antitumor antibiotics and other metabolic inhibitors. Antimicrob Agents Chemother. 1978 May;13(5):735-44. PubMed PMID: 666298; PubMed Central PMCID: PMC352325. 11: Pérez-Bustamante JA. New type of blue ternary complex of arsenazo I with plutonium (IV) in the presence of hydrogen peroxide: preliminary investigations. Talanta. 1974 Dec;21(12):1291-5. PubMed PMID: 18961599. 12: Budesínský B. Acidity of several chromotropic acid azo derivatives. Talanta. 1969 Sep;16(9):1277-88. PubMed PMID: 18960632.