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MedKoo Cat#: 597989 | Name: Boc-ypgflt(O-tbu)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Boc-ypgflt(O-tbu) is a highly delta-receptor-selective opioid antagonist.

Chemical Structure

Boc-ypgflt(O-tbu)
Boc-ypgflt(O-tbu)
CAS#179124-36-8

Theoretical Analysis

MedKoo Cat#: 597989

Name: Boc-ypgflt(O-tbu)

CAS#: 179124-36-8

Chemical Formula: C44H64N6O11

Exact Mass: 852.4633

Molecular Weight: 853.02

Elemental Analysis: C, 61.95; H, 7.56; N, 9.85; O, 20.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Boc-ypgflt(O-tbu); Boc-tyr-pro-gly-phe-leu-thr(O-t-Bu);
IUPAC/Chemical Name
N-(tert-butoxycarbonyl)-L-tyrosyl-L-prolylglycyl-L-phenylalanyl-L-leucyl-O-(tert-butyl)-L-threonine
InChi Key
MHVNVVCCPNGHGH-NYFFDOGYSA-N
InChi Code
InChI=1S/C44H64N6O11/c1-26(2)22-31(38(54)49-36(41(57)58)27(3)60-43(4,5)6)47-37(53)32(23-28-14-11-10-12-15-28)46-35(52)25-45-39(55)34-16-13-21-50(34)40(56)33(48-42(59)61-44(7,8)9)24-29-17-19-30(51)20-18-29/h10-12,14-15,17-20,26-27,31-34,36,51H,13,16,21-25H2,1-9H3,(H,45,55)(H,46,52)(H,47,53)(H,48,59)(H,49,54)(H,57,58)/t27-,31+,32+,33+,34+,36+/m1/s1
SMILES Code
C[C@@H](OC(C)(C)C)[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H](CC1=CC=CC=C1)NC(CNC([C@H]2N(C([C@H](CC3=CC=C(O)C=C3)NC(OC(C)(C)C)=O)=O)CCC2)=O)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 853.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rónai AZ, Magyar A, Orosz G, Borsodi A, Benyhe S, Tóth G, Makó E, Kátay E, Babka E, Medzihradszky K. Opioid antagonist properties of the highly delta-receptor-selective BOC-Tyr-Pro-Gly-Phe-Leu-Thr (OtBu) peptide and of its Phe1 and Mel1 analogues. Arch Int Pharmacodyn Ther. 1995 Nov-Dec;330(3):361-9. PubMed PMID: 8836454. 2: Makó E, Rónai AZ, Adám G, Juhász G, Ritter L, Lestár B, Crunelli V. Modulation by GABA(B) and delta opioid receptors of neurally induced responses in isolated guinea-pig taenia coli and human colonic circular muscle. J Physiol Paris. 2000 Mar-Apr;94(2):135-8. PubMed PMID: 10791695.