NU/ICRF 500 | CAS#156074-08-7 | topoisomerase II catalytic inhibitor

MedKoo Cat#: 597933 | Name: NU/ICRF 500

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NU/ICRF 500 is a novel anthracenyl-amino acid topoisomerase II catalytic inhibitor.

Chemical Structure

NU/ICRF 500

CAS#156074-08-7

Theoretical Analysis

MedKoo Cat#: 597933

Name: NU/ICRF 500

CAS#: 156074-08-7

Chemical Formula: C17H15N3O5

Exact Mass: 341.1012

Molecular Weight: 341.32

Elemental Analysis: C, 59.82; H, 4.43; N, 12.31; O, 23.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

NU/ICRF 500;

IUPAC/Chemical Name

(S)-3-hydroxy-2-((4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino)propanehydrazide

InChi Key

NGHSIAHRPGTXBI-NSHDSACASA-N

InChi Code

InChI=1S/C17H15N3O5/c18-20-17(25)11(7-21)19-10-5-6-12(22)14-13(10)15(23)8-3-1-2-4-9(8)16(14)24/h1-6,11,19,21-22H,7,18H2,(H,20,25)/t11-/m0/s1

SMILES Code

OC[C@@H](C(NN)=O)NC(C=CC(O)=C1C(C2=C3C=CC=C2)=O)=C1C3=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 341.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Cummings J, Sumner AT, Slavotinek A, Meikle I, Macpherson JS, Smyth JF. Cytogenetic evaluation of the mechanism of cell death induced by the novel anthracenyl-amino acid topoisomerase II catalytic inhibitor NU/ICRF 500. Mutat Res. 1995 Aug;344(1-2):55-62. PubMed PMID: 7565893.