MedKoo Cat#: 597917 | Name: Sermetacin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sermetacin is an anti-inflammatory drug.

Chemical Structure

Sermetacin
CAS#57645-05-3

Theoretical Analysis

MedKoo Cat#: 597917

Name: Sermetacin

CAS#: 57645-05-3

Chemical Formula: C22H21ClN2O6

Exact Mass: 444.1088

Molecular Weight: 444.86

Elemental Analysis: C, 59.40; H, 4.76; Cl, 7.97; N, 6.30; O, 21.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Sermetacin; SH G 318 AB; SHG 318 AB; TVX 3158; Sermetacina;
IUPAC/Chemical Name
(2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetyl)-L-serine
InChi Key
AUDFHJLSHQWFQQ-SFHVURJKSA-N
InChi Code
InChI=1S/C22H21ClN2O6/c1-12-16(10-20(27)24-18(11-26)22(29)30)17-9-15(31-2)7-8-19(17)25(12)21(28)13-3-5-14(23)6-4-13/h3-9,18,26H,10-11H2,1-2H3,(H,24,27)(H,29,30)/t18-/m0/s1
SMILES Code
OC[C@@H](C(O)=O)NC(CC1=C(C)N(C(C2=CC=C(Cl)C=C2)=O)C3=C1C=C(OC)C=C3)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 444.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tang ZZ, Lin DY. Meta-analysis for Discovering Rare-Variant Associations: Statistical Methods and Software Programs. Am J Hum Genet. 2015 Jul 2;97(1):35-53. doi: 10.1016/j.ajhg.2015.05.001. Epub 2015 Jun 18. PubMed PMID: 26094574; PubMed Central PMCID: PMC4571037. 2: Tang ZZ, Bunn P, Tao R, Liu Z, Lin DY. PreMeta: a tool to facilitate meta-analysis of rare-variant associations. BMC Genomics. 2017 Feb 14;18(1):160. doi: 10.1186/s12864-017-3573-1. PubMed PMID: 28196472; PubMed Central PMCID: PMC5310051. 3: Simino J, Wang Z, Bressler J, Chouraki V, Yang Q, Younkin SG, Seshadri S, Fornage M, Boerwinkle E, Mosley TH Jr. Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study. PLoS One. 2017 Jul 13;12(7):e0180046. doi: 10.1371/journal.pone.0180046. eCollection 2017. PubMed PMID: 28704393; PubMed Central PMCID: PMC5509141. 4: Sabo A, Mishra P, Dugan-Perez S, Voruganti VS, Kent JW Jr, Kalra D, Cole SA, Comuzzie AG, Muzny DM, Gibbs RA, Butte NF. Exome sequencing reveals novel genetic loci influencing obesity-related traits in Hispanic children. Obesity (Silver Spring). 2017 Jul;25(7):1270-1276. doi: 10.1002/oby.21869. Epub 2017 May 16. PubMed PMID: 28508493; PubMed Central PMCID: PMC5687071.