MedKoo Cat#: 572093 | Name: Bis-PEG10-NHS ester
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bis-PEG10-NHS esteris a PEG derivative containing two NHS ester groups. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PEG Linkers may be useful in the development of antibody drug conjugates.

Chemical Structure

Bis-PEG10-NHS ester
Bis-PEG10-NHS ester
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 572093

Name: Bis-PEG10-NHS ester

CAS#: NONE

Chemical Formula: C32H52N2O18

Exact Mass: 752.3215

Molecular Weight: 752.76

Elemental Analysis: C, 51.06; H, 6.96; N, 3.72; O, 38.26

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
500mg USD 950.00 2 Weeks
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Related CAS #
2221949-02-4
Synonym
Bis-PEG10-NHS ester
IUPAC/Chemical Name
bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16,19,22,25,28,31-decaoxatetratriacontanedioate
InChi Key
DWCKFVMHVUBCKY-UHFFFAOYSA-N
InChi Code
InChI=1S/C32H52N2O18/c35-27-1-2-28(36)33(27)51-31(39)5-7-41-9-11-43-13-15-45-17-19-47-21-23-49-25-26-50-24-22-48-20-18-46-16-14-44-12-10-42-8-6-32(40)52-34-29(37)3-4-30(34)38/h1-26H2
SMILES Code
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)ON(C(CC2)=O)C2=O
Appearance
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Related CAS# 1008402-79-6 (Bis-PEG9-NHS ester) The hydrophilic PEG spacer increases solubility in aqueous media.

Preparing Stock Solutions

The following data is based on the product molecular weight 752.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bonache MA, Alaimo A, Malo C, Millet O, Villarroel A, González-Muñiz R. Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding. Org Biomol Chem. 2014 Nov 28;12(44):8877-87. doi: 10.1039/c4ob01338g. PubMed PMID: 25264745. 2: Aroua S, Schweizer WB, Yamakoshi Y. C60 pyrrolidine bis-carboxylic acid derivative as a versatile precursor for biocompatible fullerenes. Org Lett. 2014 Mar 21;16(6):1688-91. doi: 10.1021/ol500363r. Epub 2014 Mar 7. PubMed PMID: 24606113. 3: Kakkar D, Tiwari AK, Chuttani K, Khanna A, Datta A, Singh H, Mishra AK. Design, synthesis, and antimycobacterial property of PEG-bis(INH) conjugates. Chem Biol Drug Des. 2012 Aug;80(2):245-53. doi: 10.1111/j.1747-0285.2012.01394.x. Epub 2012 May 30. PubMed PMID: 22515497.