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MedKoo Cat#: 597887 | Name: Hexapeptide-11

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts.

Chemical Structure

Hexapeptide-11
Hexapeptide-11
CAS#161258-30-6

Theoretical Analysis

MedKoo Cat#: 597887

Name: Hexapeptide-11

CAS#: 161258-30-6

Chemical Formula: C36H48N6O7

Exact Mass: 676.3584

Molecular Weight: 676.81

Elemental Analysis: C, 63.89; H, 7.15; N, 12.42; O, 16.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Hexapeptide-11; Peptamide 6; Fvapfp; Phe-val-ala-pro-phe-pro;
IUPAC/Chemical Name
L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-L-proline
InChi Key
GFEYWOGCSROPRT-OBXVVNIGSA-N
InChi Code
InChI=1S/C36H48N6O7/c1-22(2)30(40-31(43)26(37)20-24-12-6-4-7-13-24)33(45)38-23(3)34(46)41-18-10-16-28(41)32(44)39-27(21-25-14-8-5-9-15-25)35(47)42-19-11-17-29(42)36(48)49/h4-9,12-15,22-23,26-30H,10-11,16-21,37H2,1-3H3,(H,38,45)(H,39,44)(H,40,43)(H,48,49)/t23-,26-,27-,28-,29-,30-/m0/s1
SMILES Code
O=C(O)[C@H]1N(C([C@H](CC2=CC=CC=C2)NC([C@H]3N(C([C@H](C)NC([C@H](C(C)C)NC([C@H](CC4=CC=CC=C4)N)=O)=O)=O)CCC3)=O)=O)CCC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 676.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sklirou AD, Ralli M, Dominguez M, Papassideri I, Skaltsounis AL, Trougakos IP. Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts. Redox Biol. 2015 Aug;5:205-15. doi: 10.1016/j.redox.2015.04.010. Epub 2015 Apr 29. PubMed PMID: 25974626; PubMed Central PMCID: PMC4434199. 2: Gruber JV, Ludwig P, Holtz R. Modulation of cellular senescence in fibroblasts and dermal papillae cells in vitro. J Cosmet Sci. 2013 Mar-Apr;64(2):79-87. PubMed PMID: 23578831.

View History

GSK-2793660

GSK-2793660