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MedKoo Cat#: 597873 | Name: GF 109

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GF 109 is an ACE inhibitor.

Chemical Structure

GF 109
GF 109
CAS#79873-93-1

Theoretical Analysis

MedKoo Cat#: 597873

Name: GF 109

CAS#: 79873-93-1

Chemical Formula: C53H74N14O13

Exact Mass: 1114.5560

Molecular Weight: 1115.26

Elemental Analysis: C, 57.08; H, 6.69; N, 17.58; O, 18.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
GF 109; GF-109; GF109;
IUPAC/Chemical Name
(S)-1-(((S)-1-(L-glutamyl-L-tryptophyl)-2,5-dihydro-1H-pyrrole-2-carbonyl)-L-arginyl-L-prolyl-L-glutaminyl-L-isoleucyl-L-prolyl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid
InChi Key
DELQHVDKODCAJT-AXPLDACSSA-N
InChi Code
InChI=1S/C53H74N14O13/c1-3-29(2)43(51(78)66-25-9-16-39(66)50(77)67-26-10-17-40(67)52(79)80)63-45(72)34(19-20-41(55)68)60-46(73)37-14-7-23-64(37)48(75)35(13-6-22-58-53(56)57)61-47(74)38-15-8-24-65(38)49(76)36(62-44(71)32(54)18-21-42(69)70)27-30-28-59-33-12-5-4-11-31(30)33/h4-5,8,10-12,15,17,28-29,32,34-40,43,59H,3,6-7,9,13-14,16,18-27,54H2,1-2H3,(H2,55,68)(H,60,73)(H,61,74)(H,62,71)(H,63,72)(H,69,70)(H,79,80)(H4,56,57,58)/t29-,32-,34-,35-,36-,37-,38-,39-,40-,43-/m0/s1
SMILES Code
O=C(O)[C@H]1N(C([C@H]2N(C([C@H]([C@@H](C)CC)NC([C@H](CCC(N)=O)NC([C@H]3N(C([C@H](CCCNC(N)=N)NC([C@H]4N(C([C@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CCC(O)=O)N)=O)=O)CC=C4)=O)=O)CCC3)=O)=O)=O)CCC2)=O)CC=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,115.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Naresh S, Atreja SK. Actin Polymerization: An Event Regulated by Tyrosine Phosphorylation During Buffalo Sperm Capacitation. Reprod Domest Anim. 2015 Dec;50(6):1047-53. doi: 10.1111/rda.12635. Epub 2015 Oct 29. PubMed PMID: 26514336. 2: Hatzinikolaou P, Gavras H, Waeber B, Fisher GH, Ryan JW. Comparative study of three parenteral inhibitors of the angiotensin converting enzyme. Biochem Pharmacol. 1981 Jul 1;30(13):1869-72. PubMed PMID: 6168270.