Pyrethrosin | CAS#28272-18-6 | germacranolide

MedKoo Cat#: 592163 | Name: Pyrethrosin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyrethrosin is a germacranolide.

Chemical Structure

Pyrethrosin

CAS#28272-18-6

Theoretical Analysis

MedKoo Cat#: 592163

Name: Pyrethrosin

CAS#: 28272-18-6

Chemical Formula: C17H22O5

Exact Mass: 306.1467

Molecular Weight: 306.36

Elemental Analysis: C, 66.65; H, 7.24; O, 26.11

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Pyrethrosin; NSC 22070; NSC-22070; NSC22070

IUPAC/Chemical Name

Germacra-4,11(13)-dien-12-oic acid, 1-beta,10-epoxy-6-alpha,8-alpha-dihydroxy-, 12,8-lactone, acetate, (E)-

InChi Key

JJMLQAVFDJXJAL-JOXWODGISA-N

InChi Code

InChI=1S/C17H22O5/c1-9-5-6-14-17(4,22-14)8-13-15(10(2)16(19)21-13)12(7-9)20-11(3)18/h7,12-15H,2,5-6,8H2,1,3-4H3/b9-7+/t12-,13-,14-,15+,17+/m1/s1

SMILES Code

C/C(CC[C@@H](O1)[C@]1(C)C[C@@]2([H])OC3=O)=C\[C@@H](OC(C)=O)[C@@H]2C3=C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 306.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Mohamed ME, Pahirulzaman KA, Lazarus CM. Production of 3-Oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic Acid in the Fungus Aspergillus oryzae: A Step Towards Heterologous Production of Pyrethrins in Fungi. Mol Biotechnol. 2016 Mar;58(3):172-8. doi: 10.1007/s12033-015-9911-0. PubMed PMID: 26718544. 2: Osimitz TG, Franzosa JA, Maibach HI. Pyrethrins and pyrethrosin content in commercial allergen extracts. Dermatitis. 2009 Nov-Dec;20(6):338-40. PubMed PMID: 19958739. 3: Galal AM. Microbial transformation of pyrethrosin. J Nat Prod. 2001 Aug;64(8):1098-9. PubMed PMID: 11520238. 4: Ward MP, Armstrong RT. Surveys to assess the amount of pesticide in wool and the use of pesticides by woolgrowers in Queensland. Aust Vet J. 2001 May;79(5):358-62. PubMed PMID: 11432004. 5: Schulz KH, Hausen BM, Wallhöfer L, Schmidt-Löffler P. Chrysanthemum allergy. Pt. II: Experimental studies on the causative agents. Arch Dermatol Forsch. 1975;251(3):235-44. German. PubMed PMID: 1090264. 6: Mitchell JC, Dupuis G, Towers GH. Allergic contact dermatitis from pyrethrum (Chrysanthemum spp.). The roles of pyrethrosin, a sesquiterpene lactone, and of pyrethrin II. Br J Dermatol. 1972 Jun;86(6):568-73. PubMed PMID: 5045949.