Ige decapeptide | CAS#70669-29-3 | peptide

MedKoo Cat#: 597786 | Name: Ige decapeptide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ige decapeptide is a peptide.

Chemical Structure

Ige decapeptide

CAS#70669-29-3

Theoretical Analysis

MedKoo Cat#: 597786

Name: Ige decapeptide

CAS#: 70669-29-3

Chemical Formula: C55H80N12O13

Exact Mass: 1116.5968

Molecular Weight: 1117.31

Elemental Analysis: C, 59.12; H, 7.22; N, 15.04; O, 18.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Ige decapeptide; Immunoglobulin E decapeptide;

IUPAC/Chemical Name

L-lysyl-L-threonyl-L-lysylglycyl-L-serylglycyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-phenylalanine

InChi Key

LBWHYNPDTSNGQD-NSHCULHESA-N

InChi Code

InChI=1S/C55H80N12O13/c1-33(2)46(53(77)65-42(55(79)80)29-37-21-11-6-12-22-37)66-52(76)41(28-36-19-9-5-10-20-36)64-51(75)40(27-35-17-7-4-8-18-35)61-44(70)30-60-50(74)43(32-68)62-45(71)31-59-49(73)39(24-14-16-26-57)63-54(78)47(34(3)69)67-48(72)38(58)23-13-15-25-56/h4-12,17-22,33-34,38-43,46-47,68-69H,13-16,23-32,56-58H2,1-3H3,(H,59,73)(H,60,74)(H,61,70)(H,62,71)(H,63,78)(H,64,75)(H,65,77)(H,66,76)(H,67,72)(H,79,80)/t34-,38+,39+,40+,41+,42+,43+,46+,47+/m1/s1

SMILES Code

O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](C(C)C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CC=CC=C3)NC(CNC([C@H](CO)NC(CNC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,117.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Drake-Lee A, Jones V, Lewin I, Nayyar S, Wells A, Stanworth D. Levels of substance P and IgE decapeptide in nasal polyp fluid and matching sera: a preliminary study. J Laryngol Otol. 1996 Mar;110(3):225-7. PubMed PMID: 8730355. 2: Stanworth DR, Coleman JW, Khan Z. Essential structural requirements for triggering of mast cells by a synthetic peptide comprising a sequence in the C epsilon 4 domain of human IgE. Mol Immunol. 1984 Mar;21(3):243-7. PubMed PMID: 6425646. 3: Coleman JW, Holgate ST, Church MK, Godfrey RC. Immunoglobulin E decapeptide-induced 5-hydroxytryptamine release from rat peritoneal mast cells. Comparison with corticotropin-(1-24)-peptide, polyarginine, polylysine and antigen. Biochem J. 1981 Sep 15;198(3):615-9. PubMed PMID: 7326027; PubMed Central PMCID: PMC1163309. 4: Burt DS, Stanworth DR. Changes in cellular levels of cyclic AMP in rat mast cells during secretion of histamine induced by immunoglobulin E decapeptide and ACTH(1-24) peptide. Comparison with immunological and ionophore triggers. Biochim Biophys Acta. 1983 Jun 2;762(3):458-65. PubMed PMID: 6189527.