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MedKoo Cat#: 563261 | Name: HENC

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HENC is an inhibitor of influenza A viruses.

Chemical Structure

HENC
HENC
CAS#332170-67-9

Theoretical Analysis

MedKoo Cat#: 563261

Name: HENC

CAS#: 332170-67-9

Chemical Formula: C23H22N2O2

Exact Mass: 358.1681

Molecular Weight: 358.44

Elemental Analysis: C, 77.07; H, 6.19; N, 7.82; O, 8.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
HENC;
IUPAC/Chemical Name
3-Hydroxy-N-[(Z)-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethylideneamino]naphthalene-2-carboxamide
InChi Key
APMROBZUPYGXKE-IWIPYMOSSA-N
InChi Code
InChI=1S/C23H22N2O2/c1-15(17-11-10-16-6-2-3-7-18(16)12-17)24-25-23(27)21-13-19-8-4-5-9-20(19)14-22(21)26/h4-5,8-14,26H,2-3,6-7H2,1H3,(H,25,27)/b24-15-
SMILES Code
O=C(C1=C(O)C=C2C=CC=CC2=C1)N/N=C(C3=CC=C4CCCCC4=C3)/C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 358.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Barman S, You L, Chen R, Codrea V, Kago G, Edupuganti R, Robertus J, Krug RM, Anslyn EV. Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses. Eur J Med Chem. 2014 Jan;71:81-90. doi: 10.1016/j.ejmech.2013.10.063. Epub 2013 Nov 7. PubMed PMID: 24287556; PubMed Central PMCID: PMC4545637. 2: Kölln C, Reichl S. mRNA expression of metabolic enzymes in human cornea, corneal cell lines, and hemicornea constructs. J Ocul Pharmacol Ther. 2012 Jun;28(3):271-7. doi: 10.1089/jop.2011.0124. Epub 2011 Dec 23. PubMed PMID: 22196140; PubMed Central PMCID: PMC3361185. 3: Attama AA, Reichl S, Müller-Goymann CC. Diclofenac sodium delivery to the eye: in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct. Int J Pharm. 2008 May 1;355(1-2):307-13. doi: 10.1016/j.ijpharm.2007.12.007. Epub 2007 Dec 17. PubMed PMID: 18242022. 4: Burton GW, Wronska U, Stone L, Foster DO, Ingold KU. Biokinetics of dietary RRR-alpha-tocopherol in the male guinea pig at three dietary levels of vitamin C and two levels of vitamin E. Evidence that vitamin C does not "spare" vitamin E in vivo. Lipids. 1990 Apr;25(4):199-210. PubMed PMID: 2345493.