MedKoo Cat#: 584471 | Name: CP 43
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP 43 is a potent TAOK inhibitor.

Chemical Structure

CP 43
CP 43
CAS#850467-66-2

Theoretical Analysis

MedKoo Cat#: 584471

Name: CP 43

CAS#: 850467-66-2

Chemical Formula: C25H24N2O2

Exact Mass: 384.1838

Molecular Weight: 384.48

Elemental Analysis: C, 78.10; H, 6.29; N, 7.29; O, 8.32

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 650.00 2 Weeks
50mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
CP 43; CP43; CP-43; Compound 43 TAO Kinase Inhibitor; TAO Kinase inhibitor 1;
IUPAC/Chemical Name
N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide
InChi Key
WQKXOAJVNFOHNZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H24N2O2/c28-24(27-23-12-6-10-20-9-4-5-11-22(20)23)17-26-25(29)21-15-13-19(14-16-21)18-7-2-1-3-8-18/h1-5,7-9,11,13-16,23H,6,10,12,17H2,(H,26,29)(H,27,28)
SMILES Code
O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NCC(NC3CCCC4=C3C=CC=C4)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 384.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Koo et al (2017) Targeting TAO kinase using a new inhibitor compound delays mitosis and induces mitotic cell death in centrosome amplified breast cancer cells. Mol.Cancer Ther. 16 2410 PMID: 28830982