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MedKoo Cat#: 597750 | Name: Fpl 14294

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fpl 14294 is a novel CCK-8 agonist with potent intranasal anorectic activity in the rat.

Chemical Structure

Fpl 14294
Fpl 14294
CAS#154132-95-3

Theoretical Analysis

MedKoo Cat#: 597750

Name: Fpl 14294

CAS#: 154132-95-3

Chemical Formula: C45H56N8O13S3

Exact Mass: 1012.3129

Molecular Weight: 1013.16

Elemental Analysis: C, 53.35; H, 5.57; N, 11.06; O, 20.53; S, 9.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Fpl 14294; Fpl-14294; Fpl14294;
IUPAC/Chemical Name
(5S,11S,14S,17S)-11-((1H-indol-3-yl)methyl)-5-amino-17-((N-methyl-N-(2-(4-(sulfooxy)phenyl)acetyl)-L-phenylalanyl)carbamoyl)-14-(2-(methylthio)ethyl)-6,9,12,15-tetraoxo-2-thia-7,10,13,16-tetraazanonadecan-19-oic acid
InChi Key
OHIZQRDUJDNZHS-WZUXKDABSA-N
InChi Code
InChI=1S/C45H56N8O13S3/c1-53(39(55)22-28-13-15-30(16-14-28)66-69(63,64)65)37(21-27-9-5-4-6-10-27)45(62)52-44(61)36(24-40(56)57)51-42(59)34(18-20-68-3)50-43(60)35(23-29-25-47-33-12-8-7-11-31(29)33)49-38(54)26-48-41(58)32(46)17-19-67-2/h4-16,25,32,34-37,47H,17-24,26,46H2,1-3H3,(H,48,58)(H,49,54)(H,50,60)(H,51,59)(H,56,57)(H,52,61,62)(H,63,64,65)/t32-,34-,35-,36-,37-/m0/s1
SMILES Code
O=C(NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@H](CC1=CNC2=C1C=CC=C2)NC(CNC([C@H](CCSC)N)=O)=O)=O)=O)=O)[C@H](CC3=CC=CC=C3)N(C(CC4=CC=C(OS(=O)(O)=O)C=C4)=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,013.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Simmons RD, Blosser JC, Rosamond JR. FPL 14294: a novel CCK-8 agonist with potent intranasal anorectic activity in the rat. Pharmacol Biochem Behav. 1994 Mar;47(3):701-8. PubMed PMID: 8208791. 2: Simmons RD, Kaiser FC, Pierson ME, Rosamond JR. ARL 15849: a selective CCK-A agonist with anorectic activity in the rat and dog. Pharmacol Biochem Behav. 1998 Feb;59(2):439-44. PubMed PMID: 9476993.