Synonym
IRI-426; IRI 426; IRI426; Ac-Arg-Pro-Asp-Val-Phe-NH2;
IUPAC/Chemical Name
(S)-3-((S)-1-(acetyl-L-arginyl)pyrrolidine-2-carboxamido)-4-(((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid
InChi Key
CBRZLECMSULEQH-AQBORDMYSA-N
InChi Code
InChI=1S/C31H47N9O8/c1-17(2)25(29(47)37-21(26(32)44)15-19-9-5-4-6-10-19)39-27(45)22(16-24(42)43)38-28(46)23-12-8-14-40(23)30(48)20(36-18(3)41)11-7-13-35-31(33)34/h4-6,9-10,17,20-23,25H,7-8,11-16H2,1-3H3,(H2,32,44)(H,36,41)(H,37,47)(H,38,46)(H,39,45)(H,42,43)(H4,33,34,35)/t20-,21-,22-,23-,25-/m0/s1
SMILES Code
O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H]2N(C([C@H](CCCNC(N)=N)NC(C)=O)=O)CCC2)=O)=O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
673.77
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Thapa RK, Choi Y, Jeong JH, Youn YS, Choi HG, Yong CS, Kim JO. Folate-Mediated Targeted Delivery of Combination Chemotherapeutics Loaded Reduced Graphene Oxide for Synergistic Chemo-Photothermal Therapy of Cancers. Pharm Res. 2016 Nov;33(11):2815-27. doi: 10.1007/s11095-016-2007-0. Epub 2016 Aug 29. PubMed PMID: 27573575.
3: Mukai M, Torikata C, Iri H, Mikata A, Hanaoka H, Kato K, Kageyama K. Histogenesis of alveolar soft part sarcoma. An immunohistochemical and biochemical study. Am J Surg Pathol. 1986 Mar;10(3):212-8. PubMed PMID: 3513637.
