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MedKoo Cat#: 597712 | Name: Gdpflrfamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Gdpflrfamide is a neuropeptide found in the snail Lymnaea stagnalis.

Chemical Structure

Gdpflrfamide
Gdpflrfamide
CAS#110325-85-4

Theoretical Analysis

MedKoo Cat#: 597712

Name: Gdpflrfamide

CAS#: 110325-85-4

Chemical Formula: C41H59N11O9

Exact Mass: 849.4497

Molecular Weight: 849.99

Elemental Analysis: C, 57.94; H, 7.00; N, 18.13; O, 16.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Gdpflrfamide; Gly-asp-pro-phe-leu-arg-phe-amide; Gly-Asp-Pro-Phe-Leu-Arg-Phe-NH2
IUPAC/Chemical Name
(S)-4-((S)-2-(((S)-1-(((S)-1-(((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)pyrrolidin-1-yl)-3-(2-aminoacetamido)-4-oxobutanoic acid
InChi Key
CZDLNUYGHZETAQ-JNRWAQIZSA-N
InChi Code
InChI=1S/C41H59N11O9/c1-24(2)19-29(37(58)48-27(15-9-17-46-41(44)45)36(57)49-28(35(43)56)20-25-11-5-3-6-12-25)50-38(59)30(21-26-13-7-4-8-14-26)51-39(60)32-16-10-18-52(32)40(61)31(22-34(54)55)47-33(53)23-42/h3-8,11-14,24,27-32H,9-10,15-23,42H2,1-2H3,(H2,43,56)(H,47,53)(H,48,58)(H,49,57)(H,50,59)(H,51,60)(H,54,55)(H4,44,45,46)/t27-,28-,29-,30-,31-,32-/m0/s1
SMILES Code
O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC2=CC=CC=C2)NC([C@H]3N(C([C@H](CC(O)=O)NC(CN)=O)=O)CCC3)=O)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 849.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Skingsley DR, Bright K, Santama N, van Minnen J, Brierley MJ, Burke JF, Benjamin PR. A molecularly defined cardiorespiratory interneuron expressing SDPFLRFamide/GDPFLRFamide in the snail Lymnaea: monosynaptic connections and pharmacology. J Neurophysiol. 1993 Mar;69(3):915-27. PubMed PMID: 8096540. 2: Saunders SE, Bright K, Kellett E, Benjamin PR, Burke JF. Neuropeptides Gly-Asp-Pro-Phe-Leu-Arg-Phe-amide (GDPFLRFamide) and Ser-Asp-Pro-Phe-Leu-Arg-Phe-amide (SDPFLRFamide) are encoded by an exon 3' to Phe-Met-Arg-Phe-NH2 (FMRFamide) in the snail Lymnaea stagnalis. J Neurosci. 1991 Mar;11(3):740-5. PubMed PMID: 2002360. 3: Ebberink RH, Price DA, van Loenhout H, Doble KE, Riehm JP, Geraerts WP, Greenberg MJ. The brain of Lymnaea contains a family of FMRFamide-like peptides. Peptides. 1987 May-Jun;8(3):515-22. PubMed PMID: 3658814. 4: Nesic OB, Magoski NS, McKenney KK, Syed NI, Lukowiak K, Bulloch AG. Glutamate as a putative neurotransmitter in the mollusc, Lymnaea stagnalis. Neuroscience. 1996 Dec;75(4):1255-69. PubMed PMID: 8938758. 5: Richmond JE, Funte LR, Smith WL, Price DA, Haydon PG. Activation of a peptidergic synapse locally modulates postsynaptic calcium influx. J Exp Biol. 1991 Nov;161:257-71. PubMed PMID: 1684615. 6: Madrid KP, Price DA, Greenberg MJ, Khan HR, Saleuddin AS. FMRFamide-related peptides from the kidney of the snail, Helisoma trivolvis. Peptides. 1994 Jan;15(1):31-6. PubMed PMID: 7912428. 7: Salzet M, Bulet P, Wattez C, Malecha J. FMRFamide-related peptides in the sex segmental ganglia of the Pharyngobdellid leech Erpobdella octoculata. Identification and involvement in the control of hydric balance. Eur J Biochem. 1994 Apr 1;221(1):269-75. PubMed PMID: 8168516. 8: De Lange RP, Joosse J, Van Minnen J. Multi-messenger innervation of the male sexual system of Lymnaea stagnalis. J Comp Neurol. 1998 Jan 26;390(4):564-77. PubMed PMID: 9450536. 9: Bright K, Kellett E, Saunders SE, Brierley M, Burke JF, Benjamin PR. Mutually exclusive expression of alternatively spliced FMRFamide transcripts in identified neuronal systems of the snail Lymnaea. J Neurosci. 1993 Jun;13(6):2719-29. PubMed PMID: 8501534. 10: Buckett KJ, Dockray GJ, Osborne NN, Benjamin PR. Pharmacology of the myogenic heart of the pond snail Lymnaea stagnalis. J Neurophysiol. 1990 Jun;63(6):1413-25. PubMed PMID: 1694238. 11: Price DA, Cobb CG, Doble KE, Kline JK, Greenberg MJ. Evidence for a novel FMRFamide-related heptapeptide in the pulmonate snail Siphonaria pectinata. Peptides. 1987 May-Jun;8(3):533-8. PubMed PMID: 3658815. 12: Worster BM, Yeoman MS, Benjamin PR. Matrix-assisted laser desorption/ionization time of flight mass spectrometric analysis of the pattern of peptide expression in single neurons resulting from alternative mRNA splicing of the FMRFamide gene. Eur J Neurosci. 1998 Nov;10(11):3498-507. PubMed PMID: 9824463. 13: Bulloch AG, Price DA, Murphy AD, Lee TD, Bowes HN. FMRFamide peptides in Helisoma: identification and physiological actions at a peripheral synapse. J Neurosci. 1988 Sep;8(9):3459-69. PubMed PMID: 3171684. 14: Hoek RM, Li KW, van Minnen J, Geraerts WP. Chemical characterization of a novel peptide from the neuroendocrine light yellow cells of Lymnaea stagnalis. Brain Res Mol Brain Res. 1992 Nov;16(1-2):71-4. PubMed PMID: 1334202.

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