Synonym
Butonate; NSC 17872; NSC-17872; NSC17872
IUPAC/Chemical Name
Butanoic acid, 2,2,2-trichloro-1-(dimethoxyphosphinyl)ethyl ester
InChi Key
BKAQXYNWONVOAX-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H14Cl3O5P/c1-4-5-6(12)16-7(8(9,10)11)17(13,14-2)15-3/h7H,4-5H2,1-3H3
SMILES Code
CCCC(OC(P(OC)(OC)=O)C(Cl)(Cl)Cl)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
327.52
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Seidel F, Jahn D, Kirst E, Meeser G, Cersovsky H, Frick W. [Current views on the use of organophosphate insecticides for ectoparasitic control in lactating cattle]. Z Gesamte Hyg. 1985 Aug;31(8):470-2. German. PubMed PMID: 4060787.
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6: Gabrio T, Meeser G, Kirst E, Cersovsky H. [Studies of the Pedix Pe 50 excretion dynamics in milk]. Arch Exp Veterinarmed. 1980;34(5):713-8. German. PubMed PMID: 7458561.
7: Thiemann KG. [Residue behavior of butonate in chicken eggs]. Z Gesamte Hyg. 1979 Jul;25(7):519-21. German. PubMed PMID: 494702.
8: Ackermann H, Beitz H, Dedek W, Grahl K, Rüffle E, Georgi W, Reinhardt R. [Hygienic and toxicologic evaluation of butonate]. Z Gesamte Hyg. 1979 Jul;25(7):512-8. German. PubMed PMID: 494701.
9: Konrad H, Gabro T, Dedek W. [Behavior of selected veterinary preparations during industrial milk processing]. Nahrung. 1977;21(3):247-53. German. PubMed PMID: 404556.
10: Dedek W, Wenzel K, Schwarz H. [In-vitro and in-vivo studies on the percutaneous absorption of systemic P 32-labelled insecticide organophosphorus compounds in cattle]. Arch Exp Veterinarmed. 1975 Dec;29(6):857-68. German. PubMed PMID: 1227427.
11: Drudge JH, Lyons ET, Tolliver SC. Activity of organophosphorus compounds against oral stages of gasterophilus intestinalis and Gasterophilus nasalis. Am J Vet Res. 1975 Mar;36(3):251-3. PubMed PMID: 1115423.
12: Voss JL, Hibler CP. Critical tests of an orally administered butonate as an anthelmintic in horses. Am J Vet Res. 1973 Sep;34(9):1209-10. PubMed PMID: 4747043.
13: Voss JL, Hibler CP. Critical tests of butonate as an ascaricide and boticide in horses. Am J Vet Res. 1971 Dec;32(12):2085-6. PubMed PMID: 5167171.
14: Dedek W. [Decomposition and residues of 32P-butonate in fruit]. Z Naturforsch B. 1968 Apr;23(4):504-6. German. PubMed PMID: 4386048.
15: Dedek W, Schwarz H. [Studies on the application of the low toxicity 32P- labeled phosphonic acid ester, Butonate, in cattle]. Arch Exp Veterinarmed. 1967;21(4):1023-30. German. PubMed PMID: 5598567.
