Palmitoyl-L-aspartic acid | CAS#1782-17-8 | Hedgehog signaling inhibitor

MedKoo Cat#: 597659 | Name: Palmitoyl-L-aspartic acid

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Palmitoyl-L-aspartic acid is a natural N-acylaspartate that inhibits Hedgehog signaling after stimulation with Smoothened agonist or non-sterol-modified Sonic Hedgehog. It does not alter the activity of cannabinoid receptors or fatty acid amide hydrolase.

Chemical Structure

Palmitoyl-L-aspartic acid

CAS#1782-17-8

Theoretical Analysis

MedKoo Cat#: 597659

Name: Palmitoyl-L-aspartic acid

CAS#: 1782-17-8

Chemical Formula: C20H37NO5

Exact Mass: 371.2672

Molecular Weight: 371.52

Elemental Analysis: C, 64.66; H, 10.04; N, 3.77; O, 21.53

Price and Availability

Size	Price	Availability	Quantity
5mg	USD 450.00
10mg	USD 850.00
25mg	USD 1,350.00

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Related CAS #

No Data

Synonym

L-Aspartic acid, N-(1-oxohexadecyl)-; L-N-Palmitoylaspartic acid; Palmitoyl-L-aspartic acid;

IUPAC/Chemical Name

palmitoyl-L-aspartic acid

InChi Key

ZYJZBFYRVKLOAA-KRWDZBQOSA-N

InChi Code

InChI=1S/C20H37NO5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(22)21-17(20(25)26)16-19(23)24/h17H,2-16H2,1H3,(H,21,22)(H,23,24)(H,25,26)/t17-/m0/s1

SMILES Code

O=C(O)C[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCC)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Palmitoyl-L-aspartic acid is a natural N-acylaspartate that inhibits Hedgehog signaling after stimulation with Smoothened agonist or non-sterol-modified Sonic Hedgehog.

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	DMF	20.0	53.83
	DMSO	15.0	40.37
	Ethanol	25.0	67.29
	Methyl Acetate	10.0	26.92
	PBS (pH 7.2)	2.0	5.38

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 371.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

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