MedKoo Cat#: 597646 | Name: TH-162
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TH-162, also known as (R)​-​PIA and Adenosine, N-(1-methyl-2-phenylethyl)-, (R)- is an A1 adenosine receptor agonist. Affinity for adenosine receptor is approx. 100× that of the (+)-isomer.

Chemical Structure

TH-162
TH-162
CAS#38594-96-6

Theoretical Analysis

MedKoo Cat#: 597646

Name: TH-162

CAS#: 38594-96-6

Chemical Formula: C19H23N5O4

Exact Mass: 385.1750

Molecular Weight: 385.42

Elemental Analysis: C, 59.21; H, 6.02; N, 18.17; O, 16.60

Price and Availability

Size Price Availability Quantity
25mg USD 350.00
50mg USD 650.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
(R)​-​PIA; (R)​- PIA; (R)​-PIA; Adenosine, N-(1-methyl-2-phenylethyl)-, (R)-; L-PIA; L-2-N6-(Phenylisopropyl)adenosine; TH 162; TH-162; TH162;
IUPAC/Chemical Name
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(((R)-1-phenylpropan-2-yl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
InChi Key
RIRGCFBBHQEQQH-SSFGXONLSA-N
InChi Code
InChI=1S/C19H23N5O4/c1-11(7-12-5-3-2-4-6-12)23-17-14-18(21-9-20-17)24(10-22-14)19-16(27)15(26)13(8-25)28-19/h2-6,9-11,13,15-16,19,25-27H,7-8H2,1H3,(H,20,21,23)/t11-,13-,15-,16-,19-/m1/s1
SMILES Code
OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)N[C@H](C)CC4=CC=CC=C4)O1)O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 385.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Della Latta V, Cabiati M, Rocchiccioli S, Del Ry S, Morales MA. The role of the adenosinergic system in lung fibrosis. Pharmacol Res. 2013 Oct;76:182-9. doi: 10.1016/j.phrs.2013.08.004. Epub 2013 Aug 28. Review. PubMed PMID: 23994158.