Nph-peptide | CAS#84311-50-2 | photoaffinity labeling

MedKoo Cat#: 597583 | Name: Nph-peptide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nph-peptide is used for photoaffinity labeling of N-formyl peptide receptor site of intact human polymorphonuclear leukocytes.

Chemical Structure

Nph-peptide

CAS#84311-50-2

Theoretical Analysis

MedKoo Cat#: 597583

Name: Nph-peptide

CAS#: 84311-50-2

Chemical Formula: C55H78N12O12

Exact Mass: 1098.5862

Molecular Weight: 1099.30

Elemental Analysis: C, 60.09; H, 7.15; N, 15.29; O, 17.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Nph-peptide;

IUPAC/Chemical Name

N6-(6-((4-azido-2-nitrophenyl)amino)hexanoyl)-N2-(((S)-2-((S)-2-((S)-2-((S)-2-formamidohexanamido)-4-methylpentanamido)-3-phenylpropanamido)hexanoyl)-L-tyrosyl)-L-lysine

InChi Key

KPHWFSOLBPULFR-FQEQRRFLSA-N

InChi Code

InChI=1S/C55H78N12O12/c1-5-7-19-42(59-35-68)50(71)62-45(31-36(3)4)52(73)64-46(32-37-17-11-9-12-18-37)53(74)60-43(20-8-6-2)51(72)63-47(33-38-23-26-40(69)27-24-38)54(75)61-44(55(76)77)21-14-16-30-58-49(70)22-13-10-15-29-57-41-28-25-39(65-66-56)34-48(41)67(78)79/h9,11-12,17-18,23-28,34-36,42-47,57,69H,5-8,10,13-16,19-22,29-33H2,1-4H3,(H,58,70)(H,59,68)(H,60,74)(H,61,75)(H,62,71)(H,63,72)(H,64,73)(H,76,77)/t42-,43-,44-,45-,46-,47-/m0/s1

SMILES Code

O=C(O)[C@H](CCCCNC(CCCCCNC1=CC=C(N=[N+]=[N-])C=C1[N+]([O-])=O)=O)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CCCC)NC([C@H](CC3=CC=CC=C3)NC([C@H](CC(C)C)NC([C@H](CCCC)NC=O)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,099.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dolmatch B, Niedel J. Formyl peptide chemotactic receptor. Evidence for an active proteolytic fragment. J Biol Chem. 1983 Jun 25;258(12):7570-7. PubMed PMID: 6305946. 2: Allen RA, Jesaitis AJ, Sklar LA, Cochrane CG, Painter RG. Physicochemical properties of the N-formyl peptide receptor on human neutrophils. J Biol Chem. 1986 Feb 5;261(4):1854-7. PubMed PMID: 3944114. 3: Allen RA, Jesaitis AJ, Cochrane CG. Photoaffinity labelling of N-formyl peptide receptors. Pharmacol Ther. 1987;33(2-3):333-48. Review. PubMed PMID: 3310037. 4: Schmitt M, Painter RG, Jesaitis AJ, Preissner K, Sklar LA, Cochrane CG. Photoaffinity labeling of the N-formyl peptide receptor binding site of intact human polymorphonuclear leukocytes. A label suitable for following the fate of the receptor-ligand complex. J Biol Chem. 1983 Jan 10;258(1):649-54. PubMed PMID: 6294117.