Men 10456 | CAS#146345-90-6 | MEN 10376 derivative

MedKoo Cat#: 597563 | Name: Men 10456

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Men 10456 is the C-terminal free acid derivative of MEN 10376.

Chemical Structure

Men 10456

CAS#146345-90-6

Theoretical Analysis

MedKoo Cat#: 597563

Name: Men 10456

CAS#: 146345-90-6

Chemical Formula: C57H67N11O11

Exact Mass: 1081.5022

Molecular Weight: 1082.22

Elemental Analysis: C, 63.26; H, 6.24; N, 14.24; O, 16.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Men 10456; Men-10456; Men10456; Men 10,456; Men-10,456; Men10,456; H-Asp-tyr-D-trp-val-D-trp-D-trp-lys-OH;

IUPAC/Chemical Name

L-aspartyl-L-tyrosyl-D-tryptophyl-L-valyl-D-tryptophyl-D-tryptophyl-L-lysine

InChi Key

POGSXPZBAHMQCV-SXVLBCBNSA-N

InChi Code

InChI=1S/C57H67N11O11/c1-31(2)50(68-55(76)48(26-35-30-62-43-16-8-5-13-39(35)43)66-52(73)45(23-32-18-20-36(69)21-19-32)64-51(72)40(59)27-49(70)71)56(77)67-47(25-34-29-61-42-15-7-4-12-38(34)42)54(75)65-46(24-33-28-60-41-14-6-3-11-37(33)41)53(74)63-44(57(78)79)17-9-10-22-58/h3-8,11-16,18-21,28-31,40,44-48,50,60-62,69H,9-10,17,22-27,58-59H2,1-2H3,(H,63,74)(H,64,72)(H,65,75)(H,66,73)(H,67,77)(H,68,76)(H,70,71)(H,78,79)/t40-,44-,45-,46+,47+,48+,50-/m0/s1

SMILES Code

NCCCC[C@@H](C(O)=O)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@@H](CC3=CNC4=C3C=CC=C4)NC([C@H](C(C)C)NC([C@@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CC7=CC=C(O)C=C7)NC([C@H](CC(O)=O)N)=O)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,082.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Patacchini R, Quartara L, Rovero P, Goso C, Maggi CA. Role of C-terminal amidation on the biological activity of neurokinin A derivatives with agonist and antagonist properties. J Pharmacol Exp Ther. 1993 Jan;264(1):17-21. PubMed PMID: 8380857.