MedKoo Cat#: 597549 | Name: N2-Capryloyl lysine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

N2-Capryloyl lysine is a bioactive chemical.

Chemical Structure

N2-Capryloyl lysine
N2-Capryloyl lysine
CAS#75383-80-1

Theoretical Analysis

MedKoo Cat#: 597549

Name: N2-Capryloyl lysine

CAS#: 75383-80-1

Chemical Formula: C14H28N2O3

Exact Mass: 272.2100

Molecular Weight: 272.38

Elemental Analysis: C, 61.73; H, 10.36; N, 10.28; O, 17.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
N2-Capryloyl lysine; Octanoyl-L-lysine;
IUPAC/Chemical Name
octanoyl-L-lysine
InChi Key
GGCVGFFRMZLQBP-LBPRGKRZSA-N
InChi Code
InChI=1S/C14H28N2O3/c1-2-3-4-5-6-10-13(17)16-12(14(18)19)9-7-8-11-15/h12H,2-11,15H2,1H3,(H,16,17)(H,18,19)/t12-/m0/s1
SMILES Code
NCCCC[C@@H](C(O)=O)NC(CCCCCCC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 272.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Filippakopoulos P, Knapp S. Targeting bromodomains: epigenetic readers of lysine acetylation. Nat Rev Drug Discov. 2014 May;13(5):337-56. doi: 10.1038/nrd4286. Epub 2014 Apr 22. Review. PubMed PMID: 24751816. 2: Krzycki JA. The path of lysine to pyrrolysine. Curr Opin Chem Biol. 2013 Aug;17(4):619-25. doi: 10.1016/j.cbpa.2013.06.023. Epub 2013 Jul 12. Review. PubMed PMID: 23856058. 3: Black JC, Van Rechem C, Whetstine JR. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006. Review. PubMed PMID: 23200123; PubMed Central PMCID: PMC3861058. 4: Cimini A, Brandolini L, Gentile R, Cristiano L, Menghini P, Fidoamore A, Antonosante A, Benedetti E, Giordano A, Allegretti M. Gastroprotective effects of L-lysine salification of ketoprofen in ethanol-injured gastric mucosa. J Cell Physiol. 2015 Apr;230(4):813-20. doi: 10.1002/jcp.24809. PubMed PMID: 25287669. 5: Alam MR, Yoshizawa F, Sugahara K. Voluntary food intake variation in chickens on lysine-free diet is attributed to the plasma lysine concentration. Br Poult Sci. 2014;55(5):605-9. doi: 10.1080/00071668.2014.949623. Epub 2014 Oct 15. PubMed PMID: 25148592. 6: O'Doherty PJ, Lyons V, Tun NM, Rogers PJ, Bailey TD, Wu MJ. Transcriptomic and biochemical evidence for the role of lysine biosynthesis against linoleic acid hydroperoxide-induced stress in Saccharomyces cerevisiae. Free Radic Res. 2014 Dec;48(12):1454-61. doi: 10.3109/10715762.2014.961448. Epub 2014 Oct 18. PubMed PMID: 25184342. 7: Kroeckel S, Dietz C, Schulz C, Susenbeth A. Bioavailability of free lysine and protein-bound lysine from casein and fishmeal in juvenile turbot (Psetta maxima). Br J Nutr. 2015 Mar 14;113(5):718-27. doi: 10.1017/S000711451400381X. Epub 2015 Feb 16. PubMed PMID: 25683818. 8: Lohar S, Safin DA, Sengupta A, Chattopadhyay A, Matalobos JS, Babashkina MG, Robeyns K, Mitoraj MP, Kubisiak P, Garcia Y, Das D. Ratiometric sensing of lysine through the formation of the pyrene excimer: experimental and computational studies. Chem Commun (Camb). 2015 May 18;51(40):8536-9. doi: 10.1039/c5cc01359c. PubMed PMID: 25893984. 9: Loaëc G, Niquet-Léridon C, Henry N, Jacolot P, Jouquand C, Janssens M, Hance P, Cadalen T, Hilbert JL, Desprez B, Tessier FJ. Impact of Variety and Agronomic Factors on Crude Protein and Total Lysine in Chicory; N(ε)-Carboxymethyl-lysine-Forming Potential during Drying and Roasting. J Agric Food Chem. 2015 Dec 2;63(47):10295-302. doi: 10.1021/acs.jafc.5b02853. Epub 2015 Nov 20. PubMed PMID: 26548778. 10: Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, Hellerstein M, Goetzman ES, Gibson BW, Verdin E. SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks. Cell Metab. 2013 Dec 3;18(6):920-33. doi: 10.1016/j.cmet.2013.11.013. PubMed PMID: 24315375; PubMed Central PMCID: PMC4105152. 11: Delgado-Andrade C. Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation. Food Funct. 2016 Jan;7(1):46-57. doi: 10.1039/c5fo00918a. Review. PubMed PMID: 26462729. 12: Watkins KA, Chen R. pH-responsive, lysine-based hydrogels for the oral delivery of a wide size range of molecules. Int J Pharm. 2015 Jan 30;478(2):496-503. doi: 10.1016/j.ijpharm.2014.12.005. Epub 2014 Dec 6. PubMed PMID: 25490181. 13: Kumar KS. A chiron approach towards the synthesis of 3-hydroxy lysine and its derivatives. Bioorg Med Chem. 2013 Jun 15;21(12):3609-13. doi: 10.1016/j.bmc.2013.02.013. Epub 2013 Feb 21. PubMed PMID: 23490153. 14: Kodama Y, Nakamura T, Kurosaki T, Egashira K, Mine T, Nakagawa H, Muro T, Kitahara T, Higuchi N, Sasaki H. Biodegradable nanoparticles composed of dendrigraft poly-L-lysine for gene delivery. Eur J Pharm Biopharm. 2014 Aug;87(3):472-9. doi: 10.1016/j.ejpb.2014.04.013. Epub 2014 May 9. PubMed PMID: 24813391. 15: Szabo Z, Mena E, Rowe SP, Plyku D, Nidal R, Eisenberger MA, Antonarakis ES, Fan H, Dannals RF, Chen Y, Mease RC, Vranesic M, Bhatnagar A, Sgouros G, Cho SY, Pomper MG. Initial Evaluation of [(18)F]DCFPyL for Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer. Mol Imaging Biol. 2015 Aug;17(4):565-74. doi: 10.1007/s11307-015-0850-8. PubMed PMID: 25896814; PubMed Central PMCID: PMC4531836. 16: Roy H, Zou SB, Bullwinkle TJ, Wolfe BS, Gilreath MS, Forsyth CJ, Navarre WW, Ibba M. The tRNA synthetase paralog PoxA modifies elongation factor-P with (R)-β-lysine. Nat Chem Biol. 2011 Aug 14;7(10):667-9. doi: 10.1038/nchembio.632. PubMed PMID: 21841797; PubMed Central PMCID: PMC3177975. 17: Ishida A, Kyoya T, Nakashima K, Katsumata M. Nitrogen balance during compensatory growth when changing the levels of dietary lysine from deficiency to sufficiency in growing pigs. Anim Sci J. 2012 Nov;83(11):743-9. doi: 10.1111/j.1740-0929.2012.01018.x. Epub 2012 Apr 16. PubMed PMID: 23126327. 18: Palusiak A, Maciejewska A, Ługowski C, Różalski A. The amide of galacturonic acid with lysine as an immunodominant component of the lipopolysaccharide core region from Proteus penneri 42 strain. Acta Biochim Pol. 2014;61(1):129-32. Epub 2014 Mar 19. PubMed PMID: 24644555. 19: Chang Y, Ganesh T, Horton JR, Spannhoff A, Liu J, Sun A, Zhang X, Bedford MT, Shinkai Y, Snyder JP, Cheng X. Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J Mol Biol. 2010 Jul 2;400(1):1-7. doi: 10.1016/j.jmb.2010.04.048. Epub 2010 Apr 29. PubMed PMID: 20434463; PubMed Central PMCID: PMC2895764. 20: Pagans S, Sakane N, Schnölzer M, Ott M. Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies. Methods. 2011 Jan;53(1):91-6. doi: 10.1016/j.ymeth.2010.07.001. Epub 2010 Jul 6. PubMed PMID: 20615470; PubMed Central PMCID: PMC3478124.