Synonym
Valyllysine; Val-lys; Valyl-lysine;
IUPAC/Chemical Name
L-valyl-L-lysine
InChi Key
JKHXYJKMNSSFFL-IUCAKERBSA-N
InChi Code
InChI=1S/C11H23N3O3/c1-7(2)9(13)10(15)14-8(11(16)17)5-3-4-6-12/h7-9H,3-6,12-13H2,1-2H3,(H,14,15)(H,16,17)/t8-,9-/m0/s1
SMILES Code
NCCCC[C@@H](C(O)=O)NC([C@H](C(C)C)N)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
245.32
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Abe H, Satoh M, Miyauchi S, Shuto S, Matsuda A, Kamo N. Conjugation of dipeptide to fluorescent dyes enhances its affinity for a dipeptide transporter (PEPT1) in human intestinal Caco-2 cells. Bioconjug Chem. 1999 Jan-Feb;10(1):24-31. PubMed PMID: 9893960.
2: Tateoka R, Abe H, Miyauchi S, Shuto S, Matsuda A, Kobayashi M, Miyazaki K, Kamo N. Significance of substrate hydrophobicity for recognition by an oligopeptide transporter (PEPT1). Bioconjug Chem. 2001 Jul-Aug;12(4):485-92. PubMed PMID: 11459451.
3: Yui N, Ooya T, Kawashima T, Saito Y, Tamai I, Sai Y, Tsuji A. Inhibitory effect of supramolecular polyrotaxane-dipeptide conjugates on digested peptide uptake via intestinal human peptide transporter. Bioconjug Chem. 2002 May-Jun;13(3):582-7. PubMed PMID: 12009949.
4: Yennawar HP, Natarajan S, Viswamitra MA. Crystal and molecular structure of L-valyl-L-lysine hydrochloride. Int J Pept Protein Res. 1991 Dec;38(6):569-73. PubMed PMID: 1819591.
5: Nguyen KA, Travis J, Potempa J. Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria? J Bacteriol. 2007 Feb;189(3):833-43. Epub 2006 Dec 1. PubMed PMID: 17142394; PubMed Central PMCID: PMC1797278.
6: von Dungen A, Vater J, Kleinkauf H. Biosynthesis of gramicidin S with the aid of dipeptides by gramicidin S synthetase. Eur J Biochem. 1976 Jul 15;66(3):623-6. PubMed PMID: 60236.
