MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 597541 | Name: Pentalysine
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pentalysine is a peptide.

Chemical Structure

Pentalysine
Pentalysine
CAS#19431-21-1

Theoretical Analysis

MedKoo Cat#: 597541

Name: Pentalysine

CAS#: 19431-21-1

Chemical Formula: C30H62N10O6

Exact Mass: 658.4854

Molecular Weight: 658.89

Elemental Analysis: C, 54.69; H, 9.49; N, 21.26; O, 14.57

Price and Availability

Size Price Availability Quantity
10mg USD 500.00
50mg USD 875.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Pentalysine; Lys-lys-lys-lys-lys;
IUPAC/Chemical Name
L-lysyl-L-lysyl-L-lysyl-L-lysyl-L-lysine
InChi Key
IXPHOHNWDLRFJH-KEOOTSPTSA-N
InChi Code
InChI=1S/C30H62N10O6/c31-16-6-1-11-21(36)26(41)37-22(12-2-7-17-32)27(42)38-23(13-3-8-18-33)28(43)39-24(14-4-9-19-34)29(44)40-25(30(45)46)15-5-10-20-35/h21-25H,1-20,31-36H2,(H,37,41)(H,38,42)(H,39,43)(H,40,44)(H,45,46)/t21-,22-,23-,24-,25-/m0/s1
SMILES Code
NCCCC[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCCN)N)=O)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 658.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rieck J, Derst C, Veh RW. Polyamines (PAs) but not small peptides with closely spaced positively charged groups interact with DNA and RNA, but they do not represent a relevant buffer system at physiological pH values. PLoS One. 2024 Jul 25;19(7):e0304658. doi: 10.1371/journal.pone.0304658. PMID: 39052628; PMCID: PMC11271873. 2: Wu Z, Wang G, Li Z, Li Z, Huang D, Huang M, Lin M. Dental Bleaching with Phthalocyanine Photosensitizers: Effects on Dentin Color and Collagen Content. Molecules. 2023 May 22;28(10):4223. doi: 10.3390/molecules28104223. PMID: 37241963; PMCID: PMC10224055. 3: Leonhardt F, Gennari A, Paludo GB, Schmitz C, da Silveira FX, Moura DCDA, Renard G, Volpato G, Volken de Souza CF. A systematic review about affinity tags for one-step purification and immobilization of recombinant proteins: integrated bioprocesses aiming both economic and environmental sustainability. 3 Biotech. 2023 Jun;13(6):186. doi: 10.1007/s13205-023-03616-w. Epub 2023 May 13. PMID: 37193330; PMCID: PMC10182917. 4: Fattorini N, Maier UG. Targeting motifs in frustule-associated proteins from the centric diatom Thalassiosira pseudonana. Front Plant Sci. 2022 Oct 28;13:1006072. doi: 10.3389/fpls.2022.1006072. PMID: 36388477; PMCID: PMC9650480. 5: Chen D, Liu P, Liu Y, Wang Z, Zhou Y, Jiang L, Yuan C, Li Y, Lin W, Huang M. A Clot-Homing Near-Infrared Probe for In Vivo Imaging of Murine Thromboembolic Models. Adv Healthc Mater. 2022 Apr;11(8):e2102213. doi: 10.1002/adhm.202102213. Epub 2022 Jan 18. PMID: 34994110. 6: López-Vidal EM, Schissel CK, Mohapatra S, Bellovoda K, Wu CL, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers. JACS Au. 2021 Oct 6;1(11):2009-2020. doi: 10.1021/jacsau.1c00327. PMID: 34841414; PMCID: PMC8611673. 7: Yu S, Sun G, Sui Y, Li H, Mai Y, Wang G, Zhang N, Bi Y, Gao GF, Xu P, Jiang L, Yuan C, Yang Y, Huang M. Potent inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 by photosensitizers compounds. Dyes Pigm. 2021 Oct;194:109570. doi: 10.1016/j.dyepig.2021.109570. Epub 2021 Jun 22. PMID: 34183871; PMCID: PMC8216852. 8: Abdelhamid MAA, Meligy AMA, Yeo KB, Lee CS, Pack SP. Silaffin-3-derived pentalysine cluster as a new fusion tag for one-step immobilization and purification of recombinant Bacillus subtilis catalase on bare silica particles. Int J Biol Macromol. 2020 Sep 15;159:1103-1112. doi: 10.1016/j.ijbiomac.2020.04.172. Epub 2020 Apr 25. PMID: 32339583. 9: Disotuar MM, Petersen ME, Nogueira JM, Kay MS, Chou DH. Synthesis of hydrophobic insulin-based peptides using a helping hand strategy. Org Biomol Chem. 2019 Feb 13;17(7):1703-1708. doi: 10.1039/c8ob01212a. PMID: 29947407; PMCID: PMC6310105. 10: Cheng D, Cai W, Shao X. Understanding the Interaction Between Oligopeptide and Water in Aqueous Solution Using Temperature-Dependent Near-Infrared Spectroscopy. Appl Spectrosc. 2018 Sep;72(9):1354-1361. doi: 10.1177/0003702818769410. Epub 2018 Apr 17. PMID: 29664323. 11: Jia Y, Li J, Chen J, Hu P, Jiang L, Chen X, Huang M, Chen Z, Xu P. Smart Photosensitizer: Tumor-Triggered Oncotherapy by Self-Assembly Photodynamic Nanodots. ACS Appl Mater Interfaces. 2018 May 9;10(18):15369-15380. doi: 10.1021/acsami.7b19058. Epub 2018 Apr 24. PMID: 29652473. 12: Ullah A, Zhang Y, Iqbal Z, Zhang Y, Wang D, Chen J, Hu P, Chen Z, Huang M. Household light source for potent photo-dynamic antimicrobial effect and wound healing in an infective animal model. Biomed Opt Express. 2018 Feb 6;9(3):1006-1019. doi: 10.1364/BOE.9.001006. PMID: 29541500; PMCID: PMC5846510. 13: Geiger Y, Gottlieb HE, Akbey Ü, Oschkinat H, Goobes G. Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR. J Am Chem Soc. 2016 May 4;138(17):5561-7. doi: 10.1021/jacs.5b07809. Epub 2016 Apr 20. PMID: 26451953. 14: Rehan M, Sagar A, Sharma V, Mishra S, Ashish, Sahni G. Penta-L-lysine Potentiates Fibrin-Independent Activity of Human Tissue Plasminogen Activator. J Phys Chem B. 2015 Oct 22;119(42):13271-7. doi: 10.1021/acs.jpcb.5b07735. Epub 2015 Oct 8. PMID: 26447340. 15: Kakinoki S, Sakai Y, Fujisato T, Yamaoka T. Accelerated tissue integration into porous materials by immobilizing basic fibroblast growth factor using a biologically safe three-step reaction. J Biomed Mater Res A. 2015 Dec;103(12):3790-7. doi: 10.1002/jbm.a.35516. Epub 2015 Jun 29. PMID: 26034014. 16: Pohl A, Weiss IM. Real-time monitoring of calcium carbonate and cationic peptide deposition on carboxylate-SAM using a microfluidic SAW biosensor. Beilstein J Nanotechnol. 2014 Oct 22;5:1823-35. doi: 10.3762/bjnano.5.193. PMID: 25383294; PMCID: PMC4222353. 17: Poulsen N, Scheffel A, Sheppard VC, Chesley PM, Kröger N. Pentalysine clusters mediate silica targeting of silaffins in Thalassiosira pseudonana. J Biol Chem. 2013 Jul 12;288(28):20100-9. doi: 10.1074/jbc.M113.469379. Epub 2013 May 17. PMID: 23720751; PMCID: PMC3711277. 18: Wu J, Zawistowski A, Ehrmann M, Yi T, Schmuck C. Peptide functionalized polydiacetylene liposomes act as a fluorescent turn-on sensor for bacterial lipopolysaccharide. J Am Chem Soc. 2011 Jun 29;133(25):9720-3. doi: 10.1021/ja204013u. Epub 2011 May 31. PMID: 21615123. 19: Chen Z, Zhou S, Chen J, Deng Y, Luo Z, Chen H, Hamblin MR, Huang M. Pentalysine beta-carbonylphthalocyanine zinc: an effective tumor-targeting photosensitizer for photodynamic therapy. ChemMedChem. 2010 Jun 7;5(6):890-8. doi: 10.1002/cmdc.201000042. PMID: 20458713; PMCID: PMC2935799. 20: Kuhn-Nentwig L, Willems J, Seebeck T, Shalaby T, Kaiser M, Nentwig W. Cupiennin 1a exhibits a remarkably broad, non-stereospecific cytolytic activity on bacteria, protozoan parasites, insects, and human cancer cells. Amino Acids. 2011 Jan;40(1):69-76. doi: 10.1007/s00726-009-0471-0. Epub 2010 Feb 7. PMID: 20140690.