MedKoo Cat#: 558353 | Name: Ketopioglitazone
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ketopioglitazone is an active metabolite of pioglitazone and is found in human plasma.

Chemical Structure

Ketopioglitazone
Ketopioglitazone
CAS#146062-45-5

Theoretical Analysis

MedKoo Cat#: 558353

Name: Ketopioglitazone

CAS#: 146062-45-5

Chemical Formula: C19H18N2O4S

Exact Mass: 370.1000

Molecular Weight: 370.42

Elemental Analysis: C, 61.61; H, 4.90; N, 7.56; O, 17.28; S, 8.65

Price and Availability

Size Price Availability Quantity
5mg USD 1,150.00 2 Weeks
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Related CAS #
No Data
Synonym
Ketopioglitazone; Keto pioglitazone; Pioglitazone metabolite M3;
IUPAC/Chemical Name
5-(4-(2-(5-acetylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
InChi Key
JMLKLMFMQRAJNI-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H18N2O4S/c1-12(22)14-4-5-15(20-11-14)8-9-25-16-6-2-13(3-7-16)10-17-18(23)21-19(24)26-17/h2-7,11,17H,8-10H2,1H3,(H,21,23,24)
SMILES Code
O=C(N1)SC(CC2=CC=C(OCCC3=NC=C(C(C)=O)C=C3)C=C2)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 370.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kawaguchi-Suzuki M, Bril F, Sanchez PP, Cusi K, Frye RF. A validated liquid chromatography tandem mass spectrometry method for simultaneous determination of pioglitazone, hydroxypioglitazone, and ketopioglitazone in human plasma and its application to a clinical study. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 15;969:219-23. doi: 10.1016/j.jchromb.2014.08.019. Epub 2014 Aug 21. PubMed PMID: 25195022. 2: Vaidyanathan S, Maboudian M, Warren V, Yeh CM, Dieterich HA, Howard D, Dole WP. A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with metformin, pioglitazone and fenofibrate in healthy subjects. Curr Med Res Opin. 2008 Aug;24(8):2313-26. doi: 10.1185/03007990802259354. PubMed PMID: 18786303.