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MedKoo Cat#: 597491 | Name: Acth (7-16)NH2

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Acth (7-16)NH2 exhibits neurotrophic effects.

Chemical Structure

Acth (7-16)NH2
Acth (7-16)NH2
CAS#57241-86-8

Theoretical Analysis

MedKoo Cat#: 597491

Name: Acth (7-16)NH2

CAS#: 57241-86-8

Chemical Formula: C58H92N18O10

Exact Mass: 1200.7244

Molecular Weight: 1201.49

Elemental Analysis: C, 57.98; H, 7.72; N, 20.98; O, 13.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Acth (7-16)NH2; ACTH - (7-16)-amide;
IUPAC/Chemical Name
(S)-1-(L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl)-N-((S)-1-((2-(((S)-6-amino-1-(((S)-1,6-diamino-1-oxohexan-2-yl)amino)-1-oxohexan-2-yl)amino)-2-oxoethyl)amino)-3-methyl-1-oxobutan-2-yl)pyrrolidine-2-carboxamide
InChi Key
HTQNAQFVDAMSPJ-XAPJERKZSA-N
InChi Code
InChI=1S/C58H92N18O10/c1-35(2)49(56(85)69-34-47(77)70-42(21-9-12-26-60)53(82)72-41(50(63)79)20-8-11-25-59)75-55(84)46-24-15-29-76(46)57(86)44(22-10-13-27-61)71-48(78)33-68-52(81)45(31-37-32-67-40-19-7-6-18-38(37)40)74-54(83)43(23-14-28-66-58(64)65)73-51(80)39(62)30-36-16-4-3-5-17-36/h3-7,16-19,32,35,39,41-46,49,67H,8-15,20-31,33-34,59-62H2,1-2H3,(H2,63,79)(H,68,81)(H,69,85)(H,70,77)(H,71,78)(H,72,82)(H,73,80)(H,74,83)(H,75,84)(H4,64,65,66)/t39-,41-,42-,43-,44-,45-,46-,49-/m0/s1
SMILES Code
NCCCC[C@@H](C(N)=O)NC([C@H](CCCCN)NC(CNC([C@H](C(C)C)NC([C@H]1N(C([C@H](CCCCN)NC(CNC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@H](CCCNC(N)=N)NC([C@H](CC4=CC=CC=C4)N)=O)=O)=O)=O)=O)CCC1)=O)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,201.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wolterink G, van Ree JM. Behavioral and neurotrophic activity of ACTH-(7-16)NH2. Life Sci. 1989;45(8):703-10. PubMed PMID: 2550713. 2: Versteeg DH, Florijn WJ, Holtmaat AJ, Gispen WH, De Wildt DJ. Synchronism of pressor response and grooming behavior in freely moving, conscious rats following intracerebroventricular administration of ACTH/MSH-like peptides. Brain Res. 1993 Dec 24;631(2):265-9. PubMed PMID: 8131054.