MedKoo Cat#: 563203 | Name: SDZ-LAP-977

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SDZ-LAP-977 is an antiproliferative agent. It acts by binding to the “colchicine binding site” on tubulin and inhibiting tubulin polymerization in vitro.

Chemical Structure

SDZ-LAP-977
SDZ-LAP-977
CAS#150779-71-8

Theoretical Analysis

MedKoo Cat#: 563203

Name: SDZ-LAP-977

CAS#: 150779-71-8

Chemical Formula: C18H20O5

Exact Mass: 316.1311

Molecular Weight: 316.35

Elemental Analysis: C, 68.34; H, 6.37; O, 25.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
SDZ-LAP-977; SDZ LAP 977; SDZLAP977; SDZ281-977; LAP-977; SDZ281 977; LAP 977; SDZ281977; LAP977;
IUPAC/Chemical Name
5-[2-(2,5-Dimethoxyphenyl)ethyl]-2-hydroxy-Benzoic acid methyl ester
InChi Key
GZOFTOHENYHNMS-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H20O5/c1-21-14-7-9-17(22-2)13(11-14)6-4-12-5-8-16(19)15(10-12)18(20)23-3/h5,7-11,19H,4,6H2,1-3H3
SMILES Code
O=C(OC)C1=CC(CCC2=CC(OC)=CC=C2OC)=CC=C1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 316.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nussbaumer P, Winiski AP. Structure-activity relationship studies on a novel class of antiproliferative agents derived from Lavendustin A. Part I: Ring A modifications. Bioorg Med Chem. 2008 Aug 15;16(16):7552-60. doi: 10.1016/j.bmc.2008.07.039. Epub 2008 Jul 20. PubMed PMID: 18678497.