NVP-SAA164 | CAS#312722-60-4 | B1 receptor antagonist

MedKoo Cat#: 563185 | Name: NVP-SAA164

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NVP-SAA164 is a nonpeptide bradykinin B1 receptor antagonist.

Chemical Structure

NVP-SAA164

CAS#312722-60-4

Theoretical Analysis

MedKoo Cat#: 563185

Name: NVP-SAA164

CAS#: 312722-60-4

Chemical Formula: C36H45N5O5S

Exact Mass: 659.3141

Molecular Weight: 659.84

Elemental Analysis: C, 65.53; H, 6.87; N, 10.61; O, 12.12; S, 4.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NVP-SAA164; NVP SAA164; NVPSAA164; SAA164; SAA-164; SAA 164;

IUPAC/Chemical Name

[1-[4-(2,2-Diphenylethylamino)-3-(morpholine-4-carbonyl)phenyl]sulfonyl-piperidin-4-yl]-(4-methylpiperazin-1-yl)methanone

InChi Key

VODUCDWVPSEMSZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C36H45N5O5S/c1-38-18-20-39(21-19-38)35(42)30-14-16-41(17-15-30)47(44,45)31-12-13-34(32(26-31)36(43)40-22-24-46-25-23-40)37-27-33(28-8-4-2-5-9-28)29-10-6-3-7-11-29/h2-13,26,30,33,37H,14-25,27H2,1H3

SMILES Code

O=C(C1CCN(S(=O)(C2=CC=C(NCC(C3=CC=CC=C3)C4=CC=CC=C4)C(C(N5CCOCC5)=O)=C2)=O)CC1)N6CCN(C)CC6

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 659.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Fox A, Kaur S, Li B, Panesar M, Saha U, Davis C, Dragoni I, Colley S, Ritchie T, Bevan S, Burgess G, McIntyre P. Antihyperalgesic activity of a novel nonpeptide bradykinin B1 receptor antagonist in transgenic mice expressing the human B1 receptor. Br J Pharmacol. 2005 Apr;144(7):889-99. PubMed PMID: 15685199; PubMed Central PMCID: PMC1576084.