Ici 174865 | CAS#92535-15-4 | Delta opioid receptor antagonist

MedKoo Cat#: 597462 | Name: Ici 174865

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ici 174865 is a delta opioid receptor antagonist.

Chemical Structure

Ici 174865

CAS#92535-15-4

Theoretical Analysis

MedKoo Cat#: 597462

Name: Ici 174865

CAS#: 92535-15-4

Chemical Formula: C38H53N5O7

Exact Mass: 691.3945

Molecular Weight: 691.87

Elemental Analysis: C, 65.97; H, 7.72; N, 10.12; O, 16.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Ici 174865; Ici-174865; Ici174865; Ici 174,865; Ici-174,865; Iciq174,865;

IUPAC/Chemical Name

(2-(2-((S)-2-(diallylamino)-3-(4-hydroxyphenyl)propanamido)-2-methylpropanamido)-2-methylpropanoyl)-L-phenylalanyl-L-leucine

InChi Key

XUWLAGNFLUARAN-CHQNGUEUSA-N

InChi Code

InChI=1S/C38H53N5O7/c1-9-20-43(21-10-2)31(24-27-16-18-28(44)19-17-27)33(46)41-38(7,8)36(50)42-37(5,6)35(49)40-29(23-26-14-12-11-13-15-26)32(45)39-30(34(47)48)22-25(3)4/h9-19,25,29-31,44H,1-2,20-24H2,3-8H3,(H,39,45)(H,40,49)(H,41,46)(H,42,50)(H,47,48)/t29-,30-,31-/m0/s1

SMILES Code

CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC(C(C)(C)NC(C(C)(C)NC([C@H](CC2=CC=C(O)C=C2)N(CC=C)CC=C)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 691.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ableitner A. Brain sites involved in delta-opioid receptor-mediated actions. Eur J Pharmacol. 1994 Dec 12;271(1):213-22. PubMed PMID: 7698203. 2: Calvo CF, Cesselin F, Gelman M, Glowinski J. Identification of an opioid peptide secreted by rat embryonic mixed brain cells as a promoter of macrophage migration. Eur J Neurosci. 2000 Aug;12(8):2676-84. PubMed PMID: 10971611. 3: Maslov LN, Krylatov AV, Lishmanov AIu, Podoksenov IuK, Solenkova NV, Bogomaz SA, Tam SW, Gross GJ. [Stimulation of peripheral delta1-opioid receptors as a method of preventing ischemic and reperfusion arrhythmia: role of K(ATP)-channels]. Eksp Klin Farmakol. 2001 Nov-Dec;64(6):27-30. Russian. PubMed PMID: 11871232.