Synonym
Aminophenylacetylleucine; APAL; alpha-Aminophenylacetyl-leu;
IUPAC/Chemical Name
((S)-2-amino-2-phenylacetyl)-L-leucine
InChi Key
VJLOKXWMVJSDFY-RYUDHWBXSA-N
InChi Code
InChI=1S/C14H20N2O3/c1-9(2)8-11(14(18)19)16-13(17)12(15)10-6-4-3-5-7-10/h3-7,9,11-12H,8,15H2,1-2H3,(H,16,17)(H,18,19)/t11-,12-/m0/s1
SMILES Code
CC(C)C[C@@H](C(O)=O)NC([C@H](C1=CC=CC=C1)N)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
264.32
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Cakir OO, Yilmaz A, Demir E, Incekara K, Kose MO, Ersoy N. Association of the BsmI, ApaI, TaqI, Tru9I and FokI Polymorphisms of the Vitamin D Receptor Gene with Nephrolithiasis in the Turkish Population. Urol J. 2016 Mar 5;13(1):2509-18. PubMed PMID: 26945655.
2: de Jongh RT, Lips P, Rijs KJ, van Schoor NM, Kramer MH, Vandenbroucke JP, Dekkers OM. Associations between vitamin D receptor genotypes and mortality in a cohort of older Dutch individuals. Eur J Endocrinol. 2011 Jan;164(1):75-82. doi: 10.1530/EJE-10-0688. Epub 2010 Nov 4. PubMed PMID: 21051524.
3: O'Dell SD, Miller GJ, Cooper JA, Hindmarsh PC, Pringle PJ, Ford H, Humphries SE, Day IN. Apal polymorphism in insulin-like growth factor II (IGF2) gene and weight in middle-aged males. Int J Obes Relat Metab Disord. 1997 Sep;21(9):822-5. PubMed PMID: 9376897.
4: Forney LJ, Wong DC. Alteration of the catalytic efficiency of penicillin amidase from Escherichia coli. Appl Environ Microbiol. 1989 Oct;55(10):2556-60. PubMed PMID: 2690734; PubMed Central PMCID: PMC203121.