N-Retinoylleucine | CAS#110769-97-6 | immunological effect

MedKoo Cat#: 597449 | Name: N-Retinoylleucine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

N-Retinoylleucine has less toxicity but similar immunological effects as retinoic acid.

Chemical Structure

N-Retinoylleucine

CAS#110769-97-6

Theoretical Analysis

MedKoo Cat#: 597449

Name: N-Retinoylleucine

CAS#: 110769-97-6

Chemical Formula: C26H39NO3

Exact Mass: 413.2930

Molecular Weight: 413.60

Elemental Analysis: C, 75.50; H, 9.50; N, 3.39; O, 11.60

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

N-Retinoylleucine;

IUPAC/Chemical Name

((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoyl)-L-leucine

InChi Key

XILISIALPJYAMY-NYIXRIPJSA-N

InChi Code

InChI=1S/C26H39NO3/c1-18(2)16-23(25(29)30)27-24(28)17-20(4)11-8-10-19(3)13-14-22-21(5)12-9-15-26(22,6)7/h8,10-11,13-14,17-18,23H,9,12,15-16H2,1-7H3,(H,27,28)(H,29,30)/b11-8+,14-13+,19-10+,20-17+/t23-/m0/s1

SMILES Code

CC(C)C[C@@H](C(O)=O)NC(/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 413.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lindamood C 3rd, Dillehay DL, Lamon EW, Giles HD, Shealy YF, Sani BP, Hill DL. Toxicologic and immunologic evaluations of N-(all-trans-retinoyl)-DL-leucine and N-(all-trans-retinoyl)glycine. Toxicol Appl Pharmacol. 1988 Nov;96(2):279-95. PubMed PMID: 3194915. 2: Kochhar DM, Shealy YF, Penner JD, Jiang H. Retinamides: hydrolytic conversion of retinoylglycine to retinoic acid in pregnant mice contributes to teratogenicity. Teratology. 1992 Feb;45(2):175-85. PubMed PMID: 1615427.