MedKoo Cat#: 591976 | Name: Phenazine oxide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenazine oxide is a Fungicide, Bactericide, and Wood Preservative.

Chemical Structure

Phenazine oxide
Phenazine oxide
CAS# 304-81-4

Theoretical Analysis

MedKoo Cat#: 591976

Name: Phenazine oxide

CAS#: 304-81-4

Chemical Formula: C12H8N2O

Exact Mass: 196.0637

Molecular Weight: 196.21

Elemental Analysis: C, 73.46; H, 4.11; N, 14.28; O, 8.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Phenazine oxide
IUPAC/Chemical Name
Phenazine, 5-oxide
InChi Key
FFISWZPYNKWIRR-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H8N2O/c15-14-11-7-3-1-5-9(11)13-10-6-2-4-8-12(10)14/h1-8H
SMILES Code
[O-][N+]1=C2C=CC=CC2=NC3=C1C=CC=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 196.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Angiolini L, Valetti S, Cohen B, Feiler A, Douhal A. Fluorescence imaging of antibiotic clofazimine encapsulated within mesoporous silica particle carriers: relevance to drug delivery and the effect on its release kinetics. Phys Chem Chem Phys. 2018 May 3;20(17):11899-11911. doi: 10.1039/c7cp08328a. PubMed PMID: 29666860. 2: Jiang J, Guiza Beltran D, Schacht A, Wright S, Zhang L, Du L. Functional and Structural Analysis of Phenazine O-Methyltransferase LaPhzM from Lysobacter antibioticus OH13 and One-Pot Enzymatic Synthesis of the Antibiotic Myxin. ACS Chem Biol. 2018 Apr 20;13(4):1003-1012. doi: 10.1021/acschembio.8b00062. Epub 2018 Mar 12. PubMed PMID: 29510028; PubMed Central PMCID: PMC5910208. 3: Zhou H, Gao J, Chen Z, Duan S, Li C, Qiao R. Double-strand cleavage of DNA by a polyamide-phenazine-di-N-oxide conjugate. Bioorg Med Chem Lett. 2017 Dec 26. pii: S0960-894X(17)31232-5. doi: 10.1016/j.bmcl.2017.12.058. [Epub ahead of print] PubMed PMID: 29292228. 4: Laborda P, Zhao Y, Ling J, Hou R, Liu F. Production of Antifungal p-Aminobenzoic Acid in Lysobacter antibioticus OH13. J Agric Food Chem. 2018 Jan 24;66(3):630-636. doi: 10.1021/acs.jafc.7b05084. Epub 2018 Jan 12. PubMed PMID: 29283262. 5: de la Torre C, Domínguez-Berrocal L, Murguía JR, Marcos MD, Martínez-Máñez R, Bravo J, Sancenón F. ϵ-Polylysine-Capped Mesoporous Silica Nanoparticles as Carrier of the C9h Peptide to Induce Apoptosis in Cancer Cells. Chemistry. 2018 Feb 6;24(8):1890-1897. doi: 10.1002/chem.201704161. Epub 2018 Jan 4. PubMed PMID: 29193344. 6: Goyal PK, Verma SK, Sharma AK. Antiurolithiatic Potential of Neeri against Calcium-Oxalate Stones by Crystallization Inhibition, Free Radicals Scavenging, and NRK-52E Cell Protection from Oxalate Injury. Pharmacogn Mag. 2017 Oct;13(Suppl 3):S549-S554. doi: 10.4103/pm.pm_551_16. Epub 2017 Oct 11. PubMed PMID: 29142413; PubMed Central PMCID: PMC5669096. 7: Im CH, Kim C, Song YE, Oh SE, Jeon BH, Kim JR. Electrochemically enhanced microbial CO conversion to volatile fatty acids using neutral red as an electron mediator. Chemosphere. 2018 Jan;191:166-173. doi: 10.1016/j.chemosphere.2017.10.004. Epub 2017 Oct 3. PubMed PMID: 29032261. 8: Sahoo AK, Dash UC, Kanhar S, Mahapatra AK. In vitro biological assessment of Homalium zeylanicum and isolation of lucidenic acid A triterpenoid. Toxicol Rep. 2017 Jun 4;4:274-281. doi: 10.1016/j.toxrep.2017.04.004. eCollection 2017. PubMed PMID: 28959649; PubMed Central PMCID: PMC5615128. 9: Toyoda A, Sugiyama M, Furihata S, Nishizumi K, Omori T, Itagaki H. Development of a modified 3T3 Neutral Red Uptake Phototoxicity Test protocol for evaluation of poorly water-soluble substances. J Toxicol Sci. 2017;42(5):569-577. doi: 10.2131/jts.42.569. PubMed PMID: 28904292. 10: Wan W, Descalzo AB, Shinde S, Weißhoff H, Orellana G, Sellergren B, Rurack K. Ratiometric Fluorescence Detection of Phosphorylated Amino Acids Through Excited-State Proton Transfer by Using Molecularly Imprinted Polymer (MIP) Recognition Nanolayers. Chemistry. 2017 Nov 13;23(63):15974-15983. doi: 10.1002/chem.201703041. Epub 2017 Oct 19. PubMed PMID: 28869685. 11: Pascual L, Cerqueira-Coutinho C, García-Fernández A, de Luis B, Bernardes ES, Albernaz MS, Missailidis S, Martínez-Máñez R, Santos-Oliveira R, Orzaez M, Sancenón F. MUC1 aptamer-capped mesoporous silica nanoparticles for controlled drug delivery and radio-imaging applications. Nanomedicine. 2017 Nov;13(8):2495-2505. doi: 10.1016/j.nano.2017.08.006. Epub 2017 Aug 24. PubMed PMID: 28842375. 12: Žukovskaja O, Jahn IJ, Weber K, Cialla-May D, Popp J. Detection of Pseudomonas aeruginosa Metabolite Pyocyanin in Water and Saliva by Employing the SERS Technique. Sensors (Basel). 2017 Jul 25;17(8). pii: E1704. doi: 10.3390/s17081704. PubMed PMID: 28757555; PubMed Central PMCID: PMC5580190. 13: Rui L, Xie M, Hu B, Zhou L, Saeeduddin M, Zeng X. Enhanced solubility and antioxidant activity of chlorogenic acid-chitosan conjugates due to the conjugation of chitosan with chlorogenic acid. Carbohydr Polym. 2017 Aug 15;170:206-216. doi: 10.1016/j.carbpol.2017.04.076. Epub 2017 Apr 29. PubMed PMID: 28521988. 14: Anderson AJ, McLean JE, Jacobson AR, Britt DW. CuO and ZnO Nanoparticles Modify Interkingdom Cell Signaling Processes Relevant to Crop Production. J Agric Food Chem. 2017 May 12. doi: 10.1021/acs.jafc.7b01302. [Epub ahead of print] PubMed PMID: 28481096. 15: Valetti S, Xia X, Costa-Gouveia J, Brodin P, Bernet-Camard MF, Andersson M, Feiler A. Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections. Nanomedicine (Lond). 2017 Apr;12(8):831-844. doi: 10.2217/nnm-2016-0364. Epub 2017 Mar 24. PubMed PMID: 28338408. 16: Leonardo S, Garibo D, Fernández-Tejedor M, O'Sullivan CK, Campàs M. Addressed immobilization of biofunctionalized diatoms on electrodes by gold electrodeposition. Biofabrication. 2017 Mar 23;9(1):015027. doi: 10.1088/1758-5090/aa6400. PubMed PMID: 28332478. 17: Saidi Merzouk A, Hafida M, Medjdoub A, Loukidi B, Cherrak S, Merzouk SA, Elhabiri M. Alterations of hepatocyte function with free radical generators and reparation or prevention with coffee polyphenols. Free Radic Res. 2017 Mar;51(3):294-305. doi: 10.1080/10715762.2017.1307979. Epub 2017 Apr 9. PubMed PMID: 28301981. 18: Viktorsson EÖ, Melling Grøthe B, Aesoy R, Sabir M, Snellingen S, Prandina A, Høgmoen Åstrand OA, Bonge-Hansen T, Døskeland SO, Herfindal L, Rongved P. Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. Bioorg Med Chem. 2017 Apr 1;25(7):2285-2293. doi: 10.1016/j.bmc.2017.02.058. Epub 2017 Feb 28. PubMed PMID: 28284865. 19: Zaitseva AS, Arlyapov VA, Yudina NY, Alferov SV, Reshetilov AN. Use of one- and two-mediator systems for developing a BOD biosensor based on the yeast Debaryomyces hansenii. Enzyme Microb Technol. 2017 Mar;98:43-51. doi: 10.1016/j.enzmictec.2016.12.005. Epub 2016 Dec 26. PubMed PMID: 28110663. 20: V T F, T S C. New approach to biosensing of co-enzyme nicotinamide adenine dinucleotide (NADH) by incorporation of neutral red in aluminum doped nanostructured ZnO thin films. Biochim Biophys Acta. 2017 Jun;1861(6):1559-1565. doi: 10.1016/j.bbagen.2017.01.001. Epub 2017 Jan 4. PubMed PMID: 28062235.