MedKoo Cat#: 558346 | Name: Bibrocathol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bibrocathol is a well-established antiseptic drug for the treatment of acute eyelid diseases like blepharitis.

Chemical Structure

Bibrocathol
Bibrocathol
CAS#6915-57-7

Theoretical Analysis

MedKoo Cat#: 558346

Name: Bibrocathol

CAS#: 6915-57-7

Chemical Formula: C6HBiBr4O3

Exact Mass: 645.6500

Molecular Weight: 649.67

Elemental Analysis: C, 11.09; H, 0.16; Bi, 32.17; Br, 49.20; O, 7.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Bibrocathin; Bibrocathol; Bismucatebrol; Bismuth tetrabromopyrocatechol; Cabis bromatum; Noviform; Novoform; Posiformin; Tetrabromopyrocatechol bismuth; Tetraform.
IUPAC/Chemical Name
4,5,6,7-tetrabromobenzo[d][1,3,2]dioxabismol-2-ol
InChi Key
VTAVFIZOZUAKKE-UHFFFAOYSA-K
InChi Code
InChI=1S/C6H2Br4O2.Bi.H2O/c7-1-2(8)4(10)6(12)5(11)3(1)9;;/h11-12H;;1H2/q;+3;/p-3
SMILES Code
VTAVFIZOZUAKKE-UHFFFAOYSA-K
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 649.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bezdetko PA, Sergienko N, Dyomin Y, Korol A, Nikitin N, Merzbacher M, Groß D, Kohnen R. Successful treatment of blepharitis with bibrocathol (Posiformin® 2 %). Graefes Arch Clin Exp Ophthalmol. 2012 Dec;250(12):1869-75. doi: 10.1007/s00417-012-2001-0. Epub 2012 Apr 25. PubMed PMID: 22527308; PubMed Central PMCID: PMC3501175. 2: Behrens-Baumann W, Niederdellmann C, Jehkul A, Kohnen R. [Bibrocathol eye ointment is efficacious in blepharitis. Results from a randomized, double-blind, controlled clinical trial]. Ophthalmologe. 2006 Nov;103(11):960-5. German. PubMed PMID: 17003947. 3: WITMER R. [Vesipan (novesin-noviform, calcium pantothenicum)-eye ointment]. Schweiz Med Wochenschr. 1954 Feb 27;84(9):275. Undetermined Language. PubMed PMID: 13156533. 4: BACHMANN C. [On the complexometric determination of bismuth in Noviform]. Pharm Prax. 1961;10:178-80. German. PubMed PMID: 13863722. 5: Wictorin A, Hansson C. Allergic contact dermatitis from a bismuth compound in an eye ointment. Contact Dermatitis. 2001 Nov;45(5):318. PubMed PMID: 11722506. 6: Behrens-Baumann W, Begall T. Antiseptics versus antibiotics in the treatment of the experimental conjunctivitis caused by Staphylococcus aureus. Ger J Ophthalmol. 1993 Nov;2(6):409-11. PubMed PMID: 8312825. 7: BACHMANN C. [On the complexometric bismuth determination in noviform (B. 6 supplement)]. Pharm Prax. 1961;10:178-80. German. PubMed PMID: 13863721.