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MedKoo Cat#: 558340 | Name: Kenazepine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Kenazepine is a benzodiazepine cpd containing functional alkylating moiety. It reacts noncompetitively and irreversibly with some receptors and competitively (reversibly) with others.

Chemical Structure

Kenazepine
Kenazepine
CAS#75887-99-9

Theoretical Analysis

MedKoo Cat#: 558340

Name: Kenazepine

CAS#: 75887-99-9

Chemical Formula: C21H40N8O6

Exact Mass: 500.3100

Molecular Weight: 500.60

Elemental Analysis: C, 50.39; H, 8.05; N, 22.38; O, 19.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Kenazepine;
IUPAC/Chemical Name
Acetamide, 2-bromo-N-(2-(7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepin-1-yl)ethyl)-
InChi Key
RUMBKDGXDMTRBI-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H16BrClFN3O2/c20-10-17(26)23-7-8-25-16-6-5-12(21)9-14(16)19(24-11-18(25)27)13-3-1-2-4-15(13)22/h1-6,9H,7-8,10-11H2,(H,23,26)
SMILES Code
O=C(NCCN1C(CN=C(C2=CC=CC=C2F)C3=CC(Cl)=CC=C31)=O)CBr
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 500.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Williams EF, Rice KC, Paul SM, Skolnick P. Heterogeneity of benzodiazepine receptors in the central nervous system demonstrated with kenazepine, an alkylating benzodiazepine. J Neurochem. 1980 Sep;35(3):591-7. PubMed PMID: 6256492. 2: Williams EF, Rice KC, Mattson M, Paul SM, Skolnick P. In vivo effects of two novel alkylating benzodiazepines, irazepine and kenazepine. Pharmacol Biochem Behav. 1981 Apr;14(4):487-91. PubMed PMID: 7232472. 3: Fry JP, Rickets C, Martin IL. Polyclonal antibodies to agonist benzodiazepines. Biochem Pharmacol. 1987 Nov 1;36(21):3763-70. PubMed PMID: 2823831. 4: Sherman-Gold R, Dudai Y, Fogelfeld L, Fuchs S. Production of a high affinity antiserum to benzodiazepines. J Immunoassay. 1983;4(2):135-46. PubMed PMID: 6886014.