(-)-Inpea HCl | CAS#7388-03-6 | bioactive chemical

MedKoo Cat#: 597373 | Name: (-)-Inpea HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

(-)-Inpea HCl is a bioactive chemical.

Chemical Structure

(-)-Inpea HCl

CAS#7388-03-6

Theoretical Analysis

MedKoo Cat#: 597373

Name: (-)-Inpea HCl

CAS#: 7388-03-6

Chemical Formula: C11H17ClN2O3

Exact Mass: 260.0928

Molecular Weight: 260.71

Elemental Analysis: C, 50.68; H, 6.57; Cl, 13.60; N, 10.74; O, 18.41

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

(-)-Inpea hydrochloride; (-)-Inpea HCl; l-Inpea hydrochloride;

IUPAC/Chemical Name

(R)-2-(isopropylamino)-1-(4-nitrophenyl)ethan-1-ol hydrochloride

InChi Key

STGOXRVTUNXXLQ-MERQFXBCSA-N

InChi Code

InChI=1S/C11H16N2O3.ClH/c1-8(2)12-7-11(14)9-3-5-10(6-4-9)13(15)16;/h3-6,8,11-12,14H,7H2,1-2H3;1H/t11-;/m0./s1

SMILES Code

O[C@@H](CNC(C)C)C1=CC=C([N+]([O-])=O)C=C1.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 260.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dorfmüller P, Günther S, Ghigna MR, Thomas de Montpréville V, Boulate D, Paul JF, Jaïs X, Decante B, Simonneau G, Dartevelle P, Humbert M, Fadel E, Mercier O. Microvascular disease in chronic thromboembolic pulmonary hypertension: a role for pulmonary veins and systemic vasculature. Eur Respir J. 2014 Nov;44(5):1275-88. doi: 10.1183/09031936.00169113. Epub 2014 Aug 19. PubMed PMID: 25142477. 2: Lowenstein A. Elder abuse and neglect--"old phenomenon": new directions for research, legislation, and service developments. (2008 Rosalie S. Wolf Memorial Elder Abuse Prevention Award--International Category Lecture). J Elder Abuse Negl. 2009 Jul-Sep;21(3):278-87. doi: 10.1080/08946560902997637. PubMed PMID: 19827329. 3: Lemmens-Gruber R, Zilberszac A, Heistracher P. Arrhythmogenic effect of beta-adrenoceptor-blocking drugs in Purkinje fibres of guinea-pig hearts. Arch Int Pharmacodyn Ther. 1996 Jan-Feb;331(1):46-58. PubMed PMID: 8896710. 4: Ragazzi E, Froldi G, Fassina G. Resveratrol activity on guinea pig isolated trachea from normal and albumin-sensitized animals. Pharmacol Res Commun. 1988 Dec;20 Suppl 5:79-82. PubMed PMID: 2907791. 5: Ichiyama M, Sada S, Takahashi Y, Sada H, Ban T. Effects of bucumolol, nadolol and nifenalol on maximum upstroke velocity of action potential in guinea pig papillary muscles. Naunyn Schmiedebergs Arch Pharmacol. 1986 Mar;332(3):297-304. PubMed PMID: 2872598. 6: Gaion RM, Trento M. The role of adrenergic, purinergic and opiate receptors in the control of prostacyclin-induced contraction in the guinea-pig ileum. Arch Int Pharmacodyn Ther. 1984 Sep;271(1):33-44. PubMed PMID: 6093721. 7: Wiglusz Z, Nasal A, Damasiewicz B, Radwańska A. Possible role of ascorbic acid in catecholamines-stimulated Na+-K+-adenosine triphosphatase activity of the central nervous tissues. Pol J Pharmacol Pharm. 1984 Jul-Aug;36(4):313-21. PubMed PMID: 6152050. 8: Alinovi A, Branchetti A, Barella PA. [Iatrogenic dermatoses caused by beta-blocking drugs]. G Ital Dermatol Venereol. 1983 Nov-Dec;118(6):341-8. Review. Italian. PubMed PMID: 6143722. 9: Nishimura T, Kita S, Abiko Y. Effects of 1-(4-nitrophenyl)-2-isopropylaminoethanol (INPEA) and propranolol and their dextro-isomers on hemodynamic and metabolic responses to isoproterenol in dogs. J Pharmacol Exp Ther. 1983 Aug;226(2):595-602. PubMed PMID: 6688273. 10: Caparrotta L, Prosdocimi M, Gaion RM. Effect of diamide on isolated guinea pig atria. Pharmacol Res Commun. 1983 Jun;15(6):603-11. PubMed PMID: 6193539. 11: Pandhi P, Sharma PL. Potentiating effect of (+) INPEA on prostaglandin analogue evoked contractions of isolated rat uterus. Indian J Med Res. 1983 Mar;77:391-4. PubMed PMID: 6688239. 12: Capasso F, Sorrentino L. Sensitization by (+) Inpea of rat stomach strip contraction induced by PGE2 or pleural exudates. Pharmacol Res Commun. 1981 Jul;13(7):705-9. PubMed PMID: 6944701. 13: Sánchez-Cuadrado MC, Boada J, Bayo JM. [Action of propranolol, nifenalol, and pindolol on the lipolytic effect of adrenaline in the rat epididymis]. Arch Farmacol Toxicol. 1981 Apr;7(1):181-2. Spanish. PubMed PMID: 6895689. 14: Rossi F, Cuparencu B, DiMezza F, Lampa E, Giordano L, Quartuccio A, Marmo E. Intracarotidal injection of beta-adrenergic blocking agents: variations in the carotid sinus baro- and chemoreceptor activity. Res Commun Chem Pathol Pharmacol. 1980 Nov;30(2):211-20. PubMed PMID: 6108598. 15: Garg SK, Rajkumar K. Effect of (+) INPEA, (+) sotalol and deoxysotalol on the in vitro production of prostaglandins E and F by the rat uterus. Indian J Med Res. 1980 Apr;71:641-4. PubMed PMID: 6893041. 16: Kaumann AJ, Blinks JR. Stimulant and depressant effects of beta-adrenoceptor blocking agents on isolated heart muscle. A positive inotropic effect not mediated through andrenoceptors. Naunyn Schmiedebergs Arch Pharmacol. 1980 Apr;311(3):205-18. PubMed PMID: 6104791. 17: Orts A, Martí JL, Marco J, Baltar I, Castejón J. Effects of adrenergic blockers on platelet aggregation. Rev Esp Fisiol. 1979 Sep;35(3):269-72. PubMed PMID: 41294. 18: Kelkar VV, Gupta RS, Jariwala NU, Joshi NJ. Antagonism by some beta-adrenoceptor-blocking agents to cholinergic stimulation of skeletal muscle in vitro. Pharmacology. 1979;18(6):319-26. PubMed PMID: 40268. 19: Wepierre J, Lindenbaum A, Porquet D, Cohen Y. Hypotensive action of beta-blocking drugs injected into the cerebral ventricle of the rat. Arch Int Pharmacodyn Ther. 1978 Mar;232(1):158-65. PubMed PMID: 27151. 20: Gupta RS, Kelkar VV. Characterization of the adrenoceptor in the isolated cremaster muscle of the guinea-pig. Br J Pharmacol. 1978 Jan;62(1):3-6. PubMed PMID: 620096; PubMed Central PMCID: PMC1667781.