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MedKoo Cat#: 591898 | Name: Phenylmercuric acetate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenylmercuric acetate is a phenyl mercury compound used mainly as a fungicide. Has also been used as a herbicide, slimicide, and bacteriocide.

Chemical Structure

Phenylmercuric acetate
Phenylmercuric acetate
CAS#62-38-4

Theoretical Analysis

MedKoo Cat#: 591898

Name: Phenylmercuric acetate

CAS#: 62-38-4

Chemical Formula: C8H8HgO2

Exact Mass: 338.0231

Molecular Weight: 336.74

Elemental Analysis: Chemical Formula: C8H8HgO2 Exact Mass: 338.0231 Molecular Weight: 336.7400 Elemental Analysis: C, 28.53; H, 2.39; Hg, 59.57; O, 9.50

Price and Availability

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25g USD 350.00 2 weeks
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Synonym
Phenylmercuric acetate
IUPAC/Chemical Name
Phenylmercury acetate
InChi Key
XEBWQGVWTUSTLN-UHFFFAOYSA-M
InChi Code
InChI=1S/C6H5.C2H4O2.Hg/c1-2-4-6-5-3-1;1-2(3)4;/h1-5H;1H3,(H,3,4);/q;;+1/p-1
SMILES Code
[Hg+]C1=CC=CC=C1.CC([O-])=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
Phenylmercuric acetate is a phenyl mercury compound used mainly as a fungicide.
In vitro activity:
The in vitro activity of phenylmercuric acetate was assessed against 261 isolates of ocular pathogenic fungi that included 136 Fusarium spp. isolates, 98 Aspergillus spp. isolates, 10 Alternaria alternata isolates and 17 other pathogens. MIC₉₀s of phenylmercuric acetate were 0.0156, 0.0156, 0.0156 and 0.0156 mg/L for Fusarium spp., Aspergillus spp., A. alternata and other pathogens, respectively. MIC₉₀s of amphotericin B were 2, 2, 1 and 1 mg/L for Fusarium spp., Aspergillus spp., A. alternata and other pathogens, respectively. MIC₉₀s of natamycin were 8, 32, 4 and 4 mg/L for Fusarium spp., Aspergillus spp., A. alternata and other pathogens, respectively. Reference: J Antimicrob Chemother. 2012 Aug;67(8):1941-4. https://pubmed.ncbi.nlm.nih.gov/22514262/
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 336.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
Xu Y, Zhao D, Gao C, Zhou L, Pang G, Sun S. In vitro activity of phenylmercuric acetate against ocular pathogenic fungi. J Antimicrob Chemother. 2012 Aug;67(8):1941-4. doi: 10.1093/jac/dks133. Epub 2012 Apr 18. PMID: 22514262.
In vitro protocol:
Xu Y, Zhao D, Gao C, Zhou L, Pang G, Sun S. In vitro activity of phenylmercuric acetate against ocular pathogenic fungi. J Antimicrob Chemother. 2012 Aug;67(8):1941-4. doi: 10.1093/jac/dks133. Epub 2012 Apr 18. PMID: 22514262.
In vivo protocol:
TBD
1: LaVoie SP, Summers AO. Transcriptional responses of Escherichia coli during recovery from inorganic or organic mercury exposure. BMC Genomics. 2018 Jan 16;19(1):52. doi: 10.1186/s12864-017-4413-z. Erratum in: BMC Genomics. 2018 Apr 18;19(1):268. PubMed PMID: 29338696; PubMed Central PMCID: PMC5769350. 2: Cabral L, Yu RQ, Crane S, Giovanella P, Barkay T, Camargo FA. Methylmercury degradation by Pseudomonas putida V1. Ecotoxicol Environ Saf. 2016 Aug;130:37-42. doi: 10.1016/j.ecoenv.2016.03.036. Epub 2016 Apr 8. PubMed PMID: 27062344. 3: Salagar KM, Pujari MR, Murthy CN. A Rare Case Report of Conjunctival Cyst. J Clin Diagn Res. 2015 Nov;9(11):ND01-2. doi: 10.7860/JCDR/2015/12181.6716. Epub 2015 Nov 1. PubMed PMID: 26675748; PubMed Central PMCID: PMC4668445. 4: LaVoie SP, Mapolelo DT, Cowart DM, Polacco BJ, Johnson MK, Scott RA, Miller SM, Summers AO. Organic and inorganic mercurials have distinct effects on cellular thiols, metal homeostasis, and Fe-binding proteins in Escherichia coli. J Biol Inorg Chem. 2015 Dec;20(8):1239-51. doi: 10.1007/s00775-015-1303-1. Epub 2015 Oct 26. PubMed PMID: 26498643; PubMed Central PMCID: PMC4749482. 5: Sudhakar YA, Verma RK, Pawar SC. Type IV collagen α1-chain noncollagenous domain blocks MMP-2 activation both in-vitro and in-vivo. Sci Rep. 2014 Mar 26;4:4136. doi: 10.1038/srep04136. PubMed PMID: 24670518; PubMed Central PMCID: PMC3966261. 6: Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Enhanced activity of an angiotensin-(1-7) neuropeptidase in glucocorticoid-induced fetal programming. Peptides. 2014 Feb;52:74-81. doi: 10.1016/j.peptides.2013.12.006. Epub 2013 Dec 16. PubMed PMID: 24355101; PubMed Central PMCID: PMC4157337. 7: Cao L, Wang H, Wang F. Amyloid-β-induced matrix metalloproteinase-9 secretion is associated with retinal pigment epithelial barrier disruption. Int J Mol Med. 2013 May;31(5):1105-12. doi: 10.3892/ijmm.2013.1310. Epub 2013 Mar 20. PubMed PMID: 23525277. 8: Tezvergil-Mutluay A, Mutluay M, Seseogullari-Dirihan R, Agee KA, Key WO, Scheffel DL, Breschi L, Mazzoni A, Tjäderhane L, Nishitani Y, Tay FR, Pashley DH. Effect of phosphoric acid on the degradation of human dentin matrix. J Dent Res. 2013 Jan;92(1):87-91. doi: 10.1177/0022034512466264. Epub 2012 Oct 26. PubMed PMID: 23103634; PubMed Central PMCID: PMC3521452. 9: Xu Y, Zhao D, Gao C, Zhou L, Pang G, Sun S. In vitro activity of phenylmercuric acetate against ocular pathogenic fungi. J Antimicrob Chemother. 2012 Aug;67(8):1941-4. doi: 10.1093/jac/dks133. Epub 2012 Apr 18. PubMed PMID: 22514262. 10: Jan AT, Azam M, Ali A, Haq QM. Molecular characterization of mercury resistant bacteria inhabiting polluted water bodies of different geographical locations in India. Curr Microbiol. 2012 Jul;65(1):14-21. doi: 10.1007/s00284-012-0118-3. Epub 2012 Apr 10. PubMed PMID: 22488489. 11: Moeller TA, Shukla SJ, Xia M. Assessment of compound hepatotoxicity using human plateable cryopreserved hepatocytes in a 1536-well-plate format. Assay Drug Dev Technol. 2012 Feb;10(1):78-87. doi: 10.1089/adt.2010.0365. Epub 2011 Nov 4. PubMed PMID: 22053711; PubMed Central PMCID: PMC3277728. 12: Löwy I. 'Sexual chemistry' before the pill: science, industry and chemical contraceptives, 1920-1960. Br J Hist Sci. 2011 Jun;44(161 Pt 2):245-74. PubMed PMID: 21879607. 13: Wright C, Pilkington R, Callaghan M, McClean S. Activation of MMP-9 by human lung epithelial cells in response to the cystic fibrosis-associated pathogen Burkholderia cenocepacia reduced wound healing in vitro. Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L575-86. doi: 10.1152/ajplung.00226.2010. Epub 2011 Jul 8. PubMed PMID: 21743026. 14: Landeck L, Schalock P, Baden L, González E. Contact sensitization pattern in 172 atopic subjects. Int J Dermatol. 2011 Jul;50(7):806-10. doi: 10.1111/j.1365-4632.2010.04754.x. PubMed PMID: 21699515. 15: Bhate K, Landeck L, Gonzalez E, Neumann K, Schalock PC. Genital contact dermatitis: a retrospective analysis. Dermatitis. 2010 Nov-Dec;21(6):317-20. PubMed PMID: 21144343. 16: Durigova M, Nagase H, Mort JS, Roughley PJ. MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein. Matrix Biol. 2011 Mar;30(2):145-53. doi: 10.1016/j.matbio.2010.10.007. Epub 2010 Nov 3. PubMed PMID: 21055468; PubMed Central PMCID: PMC3057330. 17: Grierson C, Miller D, LaPan P, Brady J. Utility of combining MMP-9 enzyme-linked immunosorbent assay and MMP-9 activity assay data to monitor plasma enzyme specific activity. Anal Biochem. 2010 Sep 15;404(2):232-4. doi: 10.1016/j.ab.2010.05.020. Epub 2010 May 25. PubMed PMID: 20507826. 18: Cawston TE, Lakey RL, Rowan AD. Assay of matrix metalloproteinases against matrix substrates. Methods Mol Biol. 2010;622:245-55. doi: 10.1007/978-1-60327-299-5_15. PubMed PMID: 20135287. 19: Knäuper V, Murphy G. Methods for studying activation of matrix metalloproteinases. Methods Mol Biol. 2010;622:233-43. doi: 10.1007/978-1-60327-299-5_14. PubMed PMID: 20135286. 20: Kaur IP, Lal S, Rana C, Kakkar S, Singh H. Ocular preservatives: associated risks and newer options. Cutan Ocul Toxicol. 2009;28(3):93-103. doi: 10.1080/15569520902995834. Review. PubMed PMID: 19505226.