MedKoo Cat#: 597344 | Name: Acetyl tetrapeptide-9

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Acetyl tetrapeptide-9 plays a role in the stimulation of basement membrane polysaccharide (lumican) and the synthesis of collagen I.

Chemical Structure

Acetyl tetrapeptide-9
Acetyl tetrapeptide-9
CAS#928006-50-2

Theoretical Analysis

MedKoo Cat#: 597344

Name: Acetyl tetrapeptide-9

CAS#: 928006-50-2

Chemical Formula: C22H33N7O9

Exact Mass: 539.2340

Molecular Weight: 539.54

Elemental Analysis: C, 48.97; H, 6.17; N, 18.17; O, 26.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Acetyl tetrapeptide-9; LS 9745; LS-9745; LS9745; N-Acetyl-gln-asp-val-his; Dermican;
IUPAC/Chemical Name
(2S,5S,8S,11S)-2-((1H-imidazol-4-yl)methyl)-11-(3-amino-3-oxopropyl)-8-(carboxymethyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecanoic acid
InChi Key
QNZANUZIBYJBIN-XSWJXKHESA-N
InChi Code
InChI=1S/C22H33N7O9/c1-10(2)18(21(36)28-15(22(37)38)6-12-8-24-9-25-12)29-20(35)14(7-17(32)33)27-19(34)13(26-11(3)30)4-5-16(23)31/h8-10,13-15,18H,4-7H2,1-3H3,(H2,23,31)(H,24,25)(H,26,30)(H,27,34)(H,28,36)(H,29,35)(H,32,33)(H,37,38)/t13-,14-,15-,18-/m0/s1
SMILES Code
O=C(O)[C@H](CC1=CNC=N1)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC(C)=O)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 539.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shrestha S, Paudel P, Seong SH, Min BS, Seo EK, Jung HA, Choi JS. Two new naphthalenic lactone glycosides from Cassia obtusifolia L. seeds. Arch Pharm Res. 2018 Jun 8. doi: 10.1007/s12272-018-1044-0. [Epub ahead of print] PubMed PMID: 29948771. 2: Knox PP, Lukashev EP, Gorokhov VV, Grishanova NP, Paschenko VZ. Hybrid complexes of photosynthetic reaction centers and quantum dots in various matrices: resistance to UV irradiation and heating. Photosynth Res. 2018 Jun 15. doi: 10.1007/s11120-018-0529-5. [Epub ahead of print] PubMed PMID: 29948749. 3: Stefan A, Calonghi N, Schipani F, Dal Piaz F, Sartor G, Hochkoeppler A. Purification of active recombinant human histone deacetylase 1 (HDAC1) overexpressed in Escherichia coli. Biotechnol Lett. 2018 Jun 14. doi: 10.1007/s10529-018-2585-5. [Epub ahead of print] PubMed PMID: 29948514. 4: Song P, Yuan K, Qin T, Zhang K, Ji XJ, Ren L, Guan R, Wen J, Huang H. Metabolomics profiling reveals the mechanism of increased pneumocandin B(0) production by comparing mutant and parent strains. J Ind Microbiol Biotechnol. 2018 Jun 14. doi: 10.1007/s10295-018-2047-z. [Epub ahead of print] PubMed PMID: 29948195. 5: Ebada ME. Essential oils of green cumin and chamomile partially protect against acute acetaminophen hepatotoxicity in rats. An Acad Bras Cienc. 2018 Jun 25:0. doi: 10.1590/0001-3765201820170825. [Epub ahead of print] PubMed PMID: 29947676. 6: Claaßen C, Claaßen MH, Gohl F, Tovar GEM, Borchers K, Southan A. Photoinduced Cleavage and Hydrolysis of o-Nitrobenzyl Linker and Covalent Linker Immobilization in Gelatin Methacryloyl Hydrogels. Macromol Biosci. 2018 Jun 26:e1800104. doi: 10.1002/mabi.201800104. [Epub ahead of print] PubMed PMID: 29947093. 7: Park JK, Coffey NJ, Limoges A, Le A. The Heterogeneity of Lipid Metabolism in Cancer. Adv Exp Med Biol. 2018;1063:33-55. doi: 10.1007/978-3-319-77736-8_3. PubMed PMID: 29946774. 8: Yang Y, Zhang P, Wang Y, Wei S, Zhang L, Wang J, Lu X, Zhou H, Li R, Wen J, Zhou X, Li H, Li K, Zhao Y. Hepatoprotective Effect of San-Cao Granule on Con A-Induced Liver Injury in Mice and Mechanisms of Action Exploration. Front Pharmacol. 2018 Jun 12;9:624. doi: 10.3389/fphar.2018.00624. eCollection 2018. PubMed PMID: 29946260; PubMed Central PMCID: PMC6005824. 9: Sodhi K, Nichols A, Mallick A, Klug RL, Liu J, Wang X, Srikanthan K, Goguet-Rubio P, Nawab A, Pratt R, Lilly MN, Sanabria JR, Xie Z, Abraham NG, Shapiro JI. The Na/K-ATPase Oxidant Amplification Loop Regulates Aging. Sci Rep. 2018 Jun 26;8(1):9721. doi: 10.1038/s41598-018-26768-9. PubMed PMID: 29946187. 10: Jiang M, McMillan M, Davis VA, Kitchens CL. Phase Behavior of Acetylated Cellulose Nanocrystals and Origins of the Cross-hatch Birefringent Texture. Biomacromolecules. 2018 Jun 26. doi: 10.1021/acs.biomac.8b00746. [Epub ahead of print] PubMed PMID: 29944348. 11: Arahal DR, Lucena T, Rodrigo-Torres L, Pujalte MJ. Ruegeria denitrificans sp. nov., a marine bacterium in the family Rhodobacteraceae with the potential ability for cyanophycin synthesis. Int J Syst Evol Microbiol. 2018 Jun 26. doi: 10.1099/ijsem.0.002867. [Epub ahead of print] PubMed PMID: 29944092. 12: Jaarsma D, Blot FGC, Wu B, Venkatesan S, Voogd J, Meijer D, Ruigrok TJH, Gao Z, Schonewille M, De Zeeuw CI. The basal interstitial nucleus (BIN) of the cerebellum provides diffuse ascending inhibitory input to the floccular granule cell layer. J Comp Neurol. 2018 Jun 26. doi: 10.1002/cne.24479. [Epub ahead of print] PubMed PMID: 29943833. 13: Singh AK, Singh S, Tripathi VK, Bissoyi A, Garg G, Rizvi SI. Rapamycin confers neuroprotection against aging-induced oxidative stress, mitochondrial dysfunction and neurodegeneration in old rats via activation of autophagy. Rejuvenation Res. 2018 Jun 26. doi: 10.1089/rej.2018.2070. [Epub ahead of print] PubMed PMID: 29943667. 14: Miller EJ, Gemensky-Metzler AJ, Wilkie DA, Wynne RM, Curto EM, Chandler HL. Effects of grape seed extract, lutein, and fish oil on responses of canine lens epithelial cells in vitro. Am J Vet Res. 2018 Jul;79(7):770-778. doi: 10.2460/ajvr.79.7.770. PubMed PMID: 29943637. 15: Davoudmanesh S, Mosaabadi JM. Investigation of the effect of homocysteinylation of substance P on its binding to the NK1 receptor using molecular dynamics simulation. J Mol Model. 2018 Jun 26;24(7):177. doi: 10.1007/s00894-018-3695-7. PubMed PMID: 29943287. 16: Kou L, Du M, Liu P, Zhang B, Zhang Y, Yang P, Shang M, Wang X. Anti-Diabetic and Anti-Nephritic Activities of Grifola frondosa Mycelium Polysaccharides in Diet-Streptozotocin-Induced Diabetic Rats Via Modulation on Oxidative Stress. Appl Biochem Biotechnol. 2018 Jun 26. doi: 10.1007/s12010-018-2803-6. [Epub ahead of print] PubMed PMID: 29943275. 17: Chen Y, Huang Q, Liu W, Zhu Q, Cui CP, Xu L, Guo X, Wang P, Liu J, Dong G, Wei W, Liu CH, Feng Z, He F, Zhang L. Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth. Nat Commun. 2018 Jun 25;9(1):2464. doi: 10.1038/s41467-018-04815-3. PubMed PMID: 29942010. 18: Jin J, Richardson L, Sheller-Miller S, Zhong N, Menon R. Oxidative stress induces p38MAPK-dependent senescence in the feto-maternal interface cells. Placenta. 2018 Jul;67:15-23. doi: 10.1016/j.placenta.2018.05.008. Epub 2018 May 17. PubMed PMID: 29941169. 19: Zahoor M, Shafiq S, Ullah H, Sadiq A, Ullah F. Isolation of quercetin and mandelic acid from Aesculus indica fruit and their biological activities. BMC Biochem. 2018 Jun 26;19(1):5. doi: 10.1186/s12858-018-0095-7. PubMed PMID: 29940844. 20: Avedschmidt S, Schmidt C, Isenschmid D, Kesha K, Moons D, Gupta A. Acetyl Fentanyl: Trends and Concentrations in Metro Detroit. J Forensic Sci. 2018 Jun 25. doi: 10.1111/1556-4029.13840. [Epub ahead of print] PubMed PMID: 29940698.