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MedKoo Cat#: 597342 | Name: Alloferon 3

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Alloferon 3 is a natural peptide. It mediates signalling by NF-?B pathway to boost recognition of viral and tumor antigens. It is known to induce the production of endogenic interferons that promote a cascade of defense responses and also enhance CD25 receptor expression. Cytotoxic lymphocytes are stimulated by alloferons upon recognition of nonself or aberrant cells that are subsequently lysed.

Chemical Structure

Alloferon 3
Alloferon 3
CAS#347884-63-3

Theoretical Analysis

MedKoo Cat#: 597342

Name: Alloferon 3

CAS#: 347884-63-3

Chemical Formula: C37H54N16O12

Exact Mass: 914.4107

Molecular Weight: 914.93

Elemental Analysis: C, 48.57; H, 5.95; N, 24.49; O, 20.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Alloferon 3;
IUPAC/Chemical Name
L-valyl-L-serylglycyl-L-histidylglycyl-L-glutaminyl-L-histidylglycyl-L-histidine
InChi Key
HWFSEPIFUCDDLW-UCOKMBNGSA-N
InChi Code
InChI=1S/C37H54N16O12/c1-18(2)31(39)36(63)53-26(14-54)34(61)45-12-29(57)50-23(5-19-8-40-15-46-19)32(59)43-11-28(56)49-22(3-4-27(38)55)35(62)52-24(6-20-9-41-16-47-20)33(60)44-13-30(58)51-25(37(64)65)7-21-10-42-17-48-21/h8-10,15-18,22-26,31,54H,3-7,11-14,39H2,1-2H3,(H2,38,55)(H,40,46)(H,41,47)(H,42,48)(H,43,59)(H,44,60)(H,45,61)(H,49,56)(H,50,57)(H,51,58)(H,52,62)(H,53,63)(H,64,65)/t22-,23-,24-,25-,26-,31-/m0/s1
SMILES Code
O=C(O)[C@H](CC1=CNC=N1)NC(CNC([C@H](CC2=CNC=N2)NC([C@H](CCC(N)=O)NC(CNC([C@H](CC3=CNC=N3)NC(CNC([C@H](CO)NC([C@H](C(C)C)N)=O)=O)=O)=O)=O)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 914.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Robertson L, Rodriguez EP, Lange AB. The neural and peptidergic control of gut contraction in Locusta migratoria: the effect of an FGLa/AST. J Exp Biol. 2012 Oct 1;215(Pt 19):3394-402. doi: 10.1242/jeb.073189. Epub 2012 Jun 12. PubMed PMID: 22693021. 2: Pleskach VA, Kozhukharova IV, Alekseenko LL, Pleskach NM, Anikin VB, Chernysh SI. [Regulation of proliferation and viability of tumor cells in vitro by alloferon-1 and allostatin-1]. Tsitologiia. 2011;53(3):250-8. Russian. PubMed PMID: 21598688.