MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 597323 | Name: Hisphen

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hisphen exhibits antileukemic activity.

Chemical Structure

Hisphen
Hisphen
CAS#2764-56-9

Theoretical Analysis

MedKoo Cat#: 597323

Name: Hisphen

CAS#: 2764-56-9

Chemical Formula: C19H24Cl2N4O3

Exact Mass: 426.1225

Molecular Weight: 427.32

Elemental Analysis: C, 53.40; H, 5.66; Cl, 16.59; N, 13.11; O, 11.23

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Hisphen; Synonyms Hisfen; MD 2;
IUPAC/Chemical Name
methyl (2-(4-(bis(2-chloroethyl)amino)phenyl)acetyl)-L-histidinate
InChi Key
OKSCSVIOPIVWTC-KRWDZBQOSA-N
InChi Code
InChI=1S/C19H24Cl2N4O3/c1-28-19(27)17(11-15-12-22-13-23-15)24-18(26)10-14-2-4-16(5-3-14)25(8-6-20)9-7-21/h2-5,12-13,17H,6-11H2,1H3,(H,22,23)(H,24,26)/t17-/m0/s1
SMILES Code
O=C(OC)[C@H](CC1=CNC=N1)NC(CC2=CC=C(N(CCCl)CCCl)C=C2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 427.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Brazhenas GR, Kanopkaĭte SI, Alenene AI, Aleksene AM. [Effect of cyanocobalamin, cobamide coenzyme and the cytostatic hispen on changes in cobalamin levels in healthy rats and rats with transplanted sarcoma M-1]. Prikl Biokhim Mikrobiol. 1977 Jan-Feb;13(1):65-73. Russian. PubMed PMID: 866298. 2: Khomchenovskiĭ EI, Kershulis AA, Pauzhaĭte VI. [Antileukemic activity of p-di(2-chlorethyl)aminophenacetyl histidine methyl ester (Hisphen)]. Vopr Onkol. 1970;16(9):93. Russian. PubMed PMID: 5486447.