MedKoo Cat#: 597263 | Name: Phenylalanylglutamate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenylalanylglutamate is a dipeptide composed of phenylalanine and glutamate. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an 'Expected' metabolite.

Chemical Structure

Phenylalanylglutamate
Phenylalanylglutamate
CAS#3617-45-6

Theoretical Analysis

MedKoo Cat#: 597263

Name: Phenylalanylglutamate

CAS#: 3617-45-6

Chemical Formula: C14H18N2O5

Exact Mass: 294.1216

Molecular Weight: 294.30

Elemental Analysis: C, 57.14; H, 6.16; N, 9.52; O, 27.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Phenylalanylglutamate; Phe-glu;
IUPAC/Chemical Name
L-phenylalanyl-L-glutamic acid
InChi Key
JXWLMUIXUXLIJR-QWRGUYRKSA-N
InChi Code
InChI=1S/C14H18N2O5/c15-10(8-9-4-2-1-3-5-9)13(19)16-11(14(20)21)6-7-12(17)18/h1-5,10-11H,6-8,15H2,(H,16,19)(H,17,18)(H,20,21)/t10-,11-/m0/s1
SMILES Code
O=C(O)CC[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)N)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zaczek R, Arlis S, Markl A, Murphy T, Drucker H, Coyle JT. Characteristics of chloride-dependent incorporation of glutamate into brain membranes argue against a receptor binding site. Neuropharmacology. 1987 Apr;26(4):281-7. PubMed PMID: 2884589. 2: Kessler M, Petersen G, Vu HM, Baudry M, Lynch G. L-phenylalanyl-L-glutamate-stimulated, chloride-dependent glutamate binding represents glutamate sequestration mediated by an exchange system. J Neurochem. 1987 Apr;48(4):1191-200. PubMed PMID: 2880930. 3: Ferkany J, Zaczek R, Markl A, Coyle JT. Glutamate-containing dipeptides enhance specific binding at glutamate receptors and inhibit specific binding at kainate receptors in rat brain. Neurosci Lett. 1984 Feb 24;44(3):281-6. PubMed PMID: 6328368.