Synonym
N-Benzoyl-L-glutamic acid; L-Glutamic acid, N-benzoyl-; N-Benzoylglutamic acid;
IUPAC/Chemical Name
benzoyl-L-glutamic acid
InChi Key
LPJXPACOXRZCCP-VIFPVBQESA-N
InChi Code
InChI=1S/C12H13NO5/c14-10(15)7-6-9(12(17)18)13-11(16)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,16)(H,14,15)(H,17,18)/t9-/m0/s1
SMILES Code
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=CC=C1)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Biological target:
N-Benzoyl-L-glutamic acid is an amino acid.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
251.24
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
Formulation protocol:
TBD
1: Lough F, Perry JD, Stanforth SP, Dean JR. Determination of Carboxypeptidase Activity in Clinical Pathogens by Gas Chromatography-Mass Spectrometry. Anal Lett. 2016 May 23;49(8):1272-1277. Epub 2016 Apr 21. PubMed PMID: 27226648; PubMed Central PMCID: PMC4867780.
2: Renom G, Bruneau N, Mizon J. N-benzoyl, L-glutamic acid as a suitable internal standard for the analysis of trans,trans-muconic acid in human urine by liquid chromatography. Clin Chem Lab Med. 1998 Feb;36(2):111-3. PubMed PMID: 9594049.
3: Slama JT, Satsangi RK, Simmons A, Lynch V, Bolger RE, Suttie J. An approach to trapping gamma-glutamyl radical intermediates proposed for vitamin K dependent carboxylase: alpha,beta-methyleneglutamic acid. J Med Chem. 1990 Feb;33(2):824-32. PubMed PMID: 2299646.
4: Jensen RT, Murphy RB, Trampota M, Schneider LH, Jones SW, Howard JM, Gardner JD. Proglumide analogues: potent cholecystokinin receptor antagonists. Am J Physiol. 1985 Aug;249(2 Pt 1):G214-20. PubMed PMID: 2411147.
5: Ali M, Capindale JB. The hydrolysis of some N-acylaspartic and N-acylglutamic monoamides in dilute mineral acid. Can J Biochem. 1975 Nov;53(11):1138-44. PubMed PMID: 1192256.
