MedKoo Cat#: 597260 | Name: Monosodium N-acetylglutamate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Monosodium N-acetylglutamate is the sodium salt of N-acetylglutamate, biosynthesized from glutamate and acetylornithine by ornithine acetyltransferase, and from glutamic acid and acetyl-CoA by the enzyme N-acetylglutamate synthase. The reverse reaction, hydrolysis of the acetyl group, is catalyzed by a specific hydrolase. It is the first intermediate involved in the biosynthesis of arginine in prokaryotes and simple eukaryotes and a regulator in the process known as the urea cycle that converts toxic ammonia to urea for excretion from the body in vertebrates.

Chemical Structure

Monosodium N-acetylglutamate
Monosodium N-acetylglutamate
CAS#20640-61-3

Theoretical Analysis

MedKoo Cat#: 597260

Name: Monosodium N-acetylglutamate

CAS#: 20640-61-3

Chemical Formula: C7H10NNaO5

Exact Mass:

Molecular Weight: 211.14

Elemental Analysis: C, 39.82; H, 4.77; N, 6.63; Na, 10.89; O, 37.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Monosodium N-acetylglutamate; Sodium N-acetylglutamate (1:1);
IUPAC/Chemical Name
sodium (S)-2-acetamido-4-carboxybutanoate
InChi Key
OSORPTFXMHWGNO-JEDNCBNOSA-M
InChi Code
InChI=1S/C7H11NO5.Na/c1-4(9)8-5(7(12)13)2-3-6(10)11;/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13);/q;+1/p-1/t5-;/m0./s1
SMILES Code
O=C(O)CC[C@@H](C([O-])=O)NC(C)=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 211.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Haseleu G, Lubian E, Mueller S, Shi F, Koenig T. Quantitative studies and taste reconstitution experiments of the sour and lingering mouthful orosensation in a debittered extract of traditional Japanese dried and fermented skipjack tuna (hongarebushi). J Agric Food Chem. 2013 Apr 3;61(13):3205-11. doi: 10.1021/jf400112b. Epub 2013 Mar 19. PubMed PMID: 23472642.