MedKoo Cat#: 597241 | Name: Diopterin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Diopterin is a folic acid analog.

Chemical Structure

Diopterin
Diopterin
CAS#6807-82-5

Theoretical Analysis

MedKoo Cat#: 597241

Name: Diopterin

CAS#: 6807-82-5

Chemical Formula: C24H26N8O9

Exact Mass: 570.1823

Molecular Weight: 570.51

Elemental Analysis: C, 50.53; H, 4.59; N, 19.64; O, 25.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Diopterin; Pteroyl diglutamic acid; Folate monoglutamate;
IUPAC/Chemical Name
(4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamyl-L-glutamic acid
InChi Key
JOXCYXFULIKANJ-GJZGRUSLSA-N
InChi Code
InChI=1S/C24H26N8O9/c25-24-31-19-18(22(39)32-24)28-13(10-27-19)9-26-12-3-1-11(2-4-12)20(37)29-14(5-7-16(33)34)21(38)30-15(23(40)41)6-8-17(35)36/h1-4,10,14-15,26H,5-9H2,(H,29,37)(H,30,38)(H,33,34)(H,35,36)(H,40,41)(H3,25,27,31,32,39)/t14-,15-/m0/s1
SMILES Code
O=C(O)CC[C@@H](C(O)=O)NC([C@H](CCC(O)=O)NC(C1=CC=C(NCC2=CN=C3NC(N)=NC(C3=N2)=O)C=C1)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 570.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rothenberg SP, DaCosta M. Further observations on the folate-binding factor in some leukemic cells. J Clin Invest. 1971 Mar;50(3):719-26. PubMed PMID: 5545129; PubMed Central PMCID: PMC291980. 2: CHERRICK GR, BAKER H, FRANK O, LEEVY CM. CONVERSION OF DIOPTERIN AND TEROPTERIN INTO FOLIC AND FOLINIC ACID ACTIVITY BY THE RAT LIVER. Proc Soc Exp Biol Med. 1963 Aug-Sep;113:867-9. PubMed PMID: 14073126. 3: CURRENT medical thought on teropterin and diopterin. Am Prof Pharm. 1948 Aug;14(8):706. PubMed PMID: 18876608. 4: TEROPTERIN AND DIOPTERIN. J Am Pharm Assoc Am Pharm Assoc (Baltim). 1948 Jul;9(7):407-9. PubMed PMID: 18872616. 5: FLACK HL. Teaching responsibilities of the hospital pharmacist. Bull Am Soc Hosp Pharm. 1948 Jul-Aug;5(4):155-62. PubMed PMID: 18872606.