Hydrocinnamic acid | CAS#501-52-0 |

MedKoo Cat#: 591710 | Name: Hydrocinnamic acid

Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenylpropanoic acid or hydrocinnamic acid is a carboxylic acid with the formula C₉H₁₀O₂ belonging to the class of phenylpropanoids. It is a white, crystalline solid with a sweet, floral scent at room temperature.

Chemical Structure

Hydrocinnamic acid

CAS#501-52-0

Theoretical Analysis

MedKoo Cat#: 591710

Name: Hydrocinnamic acid

CAS#: 501-52-0

Chemical Formula: C9H10O2

Exact Mass: 150.0681

Molecular Weight: 150.18

Elemental Analysis: C, 71.98; H, 6.71; O, 21.31

Price and Availability

Size	Price	Availability	Quantity
25g	USD 350.00	2 Weeks

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

Hydrocinnamic acid; NSC 9272 NSC-9272; NSC9272

IUPAC/Chemical Name

3-Phenylpropionic acid

InChi Key

XMIIGOLPHOKFCH-UHFFFAOYSA-N

InChi Code

InChI=1S/C9H10O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,11)

SMILES Code

O=C(O)CCC1=CC=CC=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 150.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Li Z, Li Y, Zhang Y, Cheng B, Peng Y, Zhang X, Ma X, Huang L, Yan Y. Indole-3-acetic acid modulates phytohormones and polyamines metabolism associated with the tolerance to water stress in white clover. Plant Physiol Biochem. 2018 Jun 9;129:251-263. doi: 10.1016/j.plaphy.2018.06.009. [Epub ahead of print] PubMed PMID: 29906775. 2: Neamatallah T, El-Shitany NA, Abbas AT, Ali SS, Eid BG. Honey protects against cisplatin-induced hepatic and renal toxicity through inhibition of NF-κB-mediated COX-2 expression and the oxidative stress dependent BAX/Bcl-2/caspase-3 apoptotic pathway. Food Funct. 2018 Jun 13. doi: 10.1039/c8fo00653a. [Epub ahead of print] PubMed PMID: 29897076. 3: Zhu YB, Xu Y, Wang LM, Qi B. Biosynthesis of (R)-2-hydroxy-3-phenylpropionic acid using whole recombinant Escherichia coli cells in an aqueous/n-octane biphasic system. J Zhejiang Univ Sci B. 2018 Apr.;19(4):285-292. doi: 10.1631/jzus.B1700040. PubMed PMID: 29616504; PubMed Central PMCID: PMC5964342. 4: Rath M, Mitchell TR, Gold SE. Volatiles produced by Bacillus mojavensis RRC101 act as plant growth modulators and are strongly culture-dependent. Microbiol Res. 2018 Mar;208:76-84. doi: 10.1016/j.micres.2017.12.014. Epub 2018 Jan 3. PubMed PMID: 29551214. 5: Sadeghi Ekbatan S, Li XQ, Ghorbani M, Azadi B, Kubow S. Chlorogenic Acid and Its Microbial Metabolites Exert Anti-Proliferative Effects, S-Phase Cell-Cycle Arrest and Apoptosis in Human Colon Cancer Caco-2 Cells. Int J Mol Sci. 2018 Mar 3;19(3). pii: E723. doi: 10.3390/ijms19030723. PubMed PMID: 29510500; PubMed Central PMCID: PMC5877584. 6: Gao X, Tang J, Liu H, Liu L, Kang L, Chen W. Structure-activity relationship investigation of tertiary amine derivatives of cinnamic acid as acetylcholinesterase and butyrylcholinesterase inhibitors: compared with that of phenylpropionic acid, sorbic acid and hexanoic acid. J Enzyme Inhib Med Chem. 2018 Dec;33(1):519-524. doi: 10.1080/14756366.2018.1436053. PubMed PMID: 29447012. 7: Rab E, Kekos D, Roussis V, Ioannou E. α-Pyrone Polyketides from Streptomyces ambofaciens BI0048, an Endophytic Actinobacterial Strain Isolated from the Red Alga Laurencia glandulifera. Mar Drugs. 2017 Dec 14;15(12). pii: E389. doi: 10.3390/md15120389. PubMed PMID: 29240664; PubMed Central PMCID: PMC5742849. 8: Vollmer M, Esders S, Farquharson FM, Neugart S, Duncan SH, Schreiner M, Louis P, Maul R, Rohn S. Mutual Interaction of Phenolic Compounds and Microbiota: Metabolism of Complex Phenolic Apigenin-C- and Kaempferol-O-Derivatives by Human Fecal Samples. J Agric Food Chem. 2018 Jan 17;66(2):485-497. doi: 10.1021/acs.jafc.7b04842. Epub 2018 Jan 3. PubMed PMID: 29236499. 9: Li Y, Li S, Lin SJ, Zhang JJ, Zhao CN, Li HB. Microwave-Assisted Extraction of Natural Antioxidants from the Exotic Gordonia axillaris Fruit: Optimization and Identification of Phenolic Compounds. Molecules. 2017 Sep 6;22(9). pii: E1481. doi: 10.3390/molecules22091481. PubMed PMID: 28878178. 10: Tehrani KHME, Martin NI. Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem. ACS Infect Dis. 2017 Oct 13;3(10):711-717. doi: 10.1021/acsinfecdis.7b00094. Epub 2017 Aug 28. PubMed PMID: 28820574; PubMed Central PMCID: PMC5644712. 11: Toyao T, Siddiki SMAH, Morita Y, Kamachi T, Touchy AS, Onodera W, Kon K, Furukawa S, Ariga H, Asakura K, Yoshizawa K, Shimizu KI. Rhenium-Loaded TiO(2) : A Highly Versatile and Chemoselective Catalyst for the Hydrogenation of Carboxylic Acid Derivatives and the N-Methylation of Amines Using H(2) and CO(2). Chemistry. 2017 Oct 20;23(59):14848-14859. doi: 10.1002/chem.201702801. Epub 2017 Sep 26. PubMed PMID: 28815903. 12: Bhat FM, Riar CS. Extraction, identification and assessment of antioxidative compounds of bran extracts of traditional rice cultivars: An analytical approach. Food Chem. 2017 Dec 15;237:264-274. doi: 10.1016/j.foodchem.2017.05.113. Epub 2017 May 23. PubMed PMID: 28763995. 13: Ren S, Pang C, Huang Y, Xing C, Zhan Y, An H. Hydrocinnamic Acid Inhibits the Currents of WT and SQT3 Syndrome-Related Mutants of Kir2.1 Channel. J Membr Biol. 2017 Oct;250(5):425-432. doi: 10.1007/s00232-017-9964-z. Epub 2017 Jun 28. PubMed PMID: 28660286. 14: Zhang X, Cai C, Winters M, Wells M, Wall M, Lanter J, Sui Z, Ma J, Novack A, Nashashibi I, Wang Y, Yan W, Suckow A, Hua H, Bell A, Haug P, Clapper W, Jenkinson C, Gunnet J, Leonard J, Murray WV. Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3272-3278. doi: 10.1016/j.bmcl.2017.06.028. Epub 2017 Jun 12. PubMed PMID: 28642104. 15: Weng J, Cai B, Chen J, Chen B, Wu H, Wen C, Sun F, Hu L, Chen C, Wang X, Wang Z. Metabolic changes in methomyl poisoned rats treated by vitamin E. Hum Exp Toxicol. 2018 Apr;37(4):390-398. doi: 10.1177/0960327117705428. Epub 2017 Apr 20. PubMed PMID: 28425351. 16: Ohshima M, Sugahara K, Kasahara K, Katakura A. Metabolomic analysis of the saliva of Japanese patients with oral squamous cell carcinoma. Oncol Rep. 2017 May;37(5):2727-2734. doi: 10.3892/or.2017.5561. Epub 2017 Apr 6. PubMed PMID: 28393236. 17: Yu D, Zhou F, Lim DS, Su H, Zhang Y. NHC-Ag/Pd-Catalyzed Reductive Carboxylation of Terminal Alkynes with CO(2) and H(2) : A Combined Experimental and Computational Study for Fine-Tuned Selectivity. ChemSusChem. 2017 Mar 9;10(5):836-841. doi: 10.1002/cssc.201601785. Epub 2017 Feb 10. PubMed PMID: 28044419. 18: Zgani I, Idriss H, Barbot C, Djedaïni-Pilard F, Petit S, Hubert-Roux M, Estour F, Gouhier G. Positive variation of the MRI signal via intramolecular inclusion complexation of a C-2 functionalized β-cyclodextrin. Org Biomol Chem. 2017 Jan 18;15(3):564-569. doi: 10.1039/c6ob02583h. PubMed PMID: 27991631. 19: Toyao T, Siddiki SM, Touchy AS, Onodera W, Kon K, Morita Y, Kamachi T, Yoshizawa K, Shimizu KI. TiO(2) -Supported Re as a General and Chemoselective Heterogeneous Catalyst for Hydrogenation of Carboxylic Acids to Alcohols. Chemistry. 2017 Jan 23;23(5):1001-1006. doi: 10.1002/chem.201604762. Epub 2016 Nov 22. PubMed PMID: 27874230. 20: Li ZB, Zhou RJ, Xie YJ, Fu JF. [Allelopathic effects of phenolic compounds of ginseng root rhizosphere on Cylindrocarpon destructans.]. Ying Yong Sheng Tai Xue Bao. 2016 Nov 18;27(11):3616-3622. doi: 10.13287/j.1001-9332.201611.002. Chinese. PubMed PMID: 29696860.