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MedKoo Cat#: 591706 | Name: Mequinol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mequinol is a Depigmenting agent.

Chemical Structure

Mequinol
Mequinol
CAS#150-76-5

Theoretical Analysis

MedKoo Cat#: 591706

Name: Mequinol

CAS#: 150-76-5

Chemical Formula: C7H8O2

Exact Mass: 124.0524

Molecular Weight: 124.14

Elemental Analysis: C, 67.73; H, 6.50; O, 25.78

Price and Availability

Size Price Availability Quantity
100g USD 250.00 2 weeks
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Related CAS #
No Data
Synonym
Mequinol; NSC 4960; NSC-4960; NSC4960, Hydroquinone Monomethyl Ether, 4-Hydroxyanisole, MEHQ
IUPAC/Chemical Name
4-Methoxyphenol
InChi Key
NWVVVBRKAWDGAB-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H8O2/c1-9-7-4-2-6(8)3-5-7/h2-5,8H,1H3
SMILES Code
OC1=CC=C(OC)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
Mequinol (4-Methoxyphenol) is one of bioactive components in Mercurialis.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
Ethanol 25.0 201.39
Water 62.5 503.47
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 124.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
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Inhibitory effects of p-cresol and p-hydroxy anisole dimers on expression of the cyclooxygenase-2 gene and lipopolysaccharide-stimulated activation of nuclear factor-κB in RAW264.7 cells. In Vivo. 2014 Sep-Oct;28(5):719-25. PubMed PMID: 25189882. 12: Zaky AM, Chaplin BP. Mechanism of p-substituted phenol oxidation at a Ti4O7 reactive electrochemical membrane. Environ Sci Technol. 2014 May 20;48(10):5857-67. doi: 10.1021/es5010472. Epub 2014 May 8. PubMed PMID: 24766505. 13: Wang TJ, An J, Chen XH, Deng QD, Yang L. Assessment of Cuscuta chinensis seeds׳ effect on melanogenesis: comparison of water and ethanol fractions in vitro and in vivo. J Ethnopharmacol. 2014 May 28;154(1):240-8. doi: 10.1016/j.jep.2014.04.016. Epub 2014 Apr 16. PubMed PMID: 24746484. 14: Hadden DJ, Roberts GM, Karsili TN, Ashfold MN, Stavros VG. Competing 1πσ* mediated dynamics in mequinol: O-H versus O-CH3 photodissociation pathways. Phys Chem Chem Phys. 2012 Oct 14;14(38):13415-28. doi: 10.1039/c2cp42289a. PubMed PMID: 22948565. 15: Luzy AP, Orsini N, Linget JM, Bouvier G. Evaluation of the GADD45α-GFP GreenScreen HC assay for rapid and reliable in vitro early genotoxicity screening. J Appl Toxicol. 2013 Nov;33(11):1303-15. doi: 10.1002/jat.2793. Epub 2012 Jul 13. PubMed PMID: 22806210. 16: Rossi AM, Perez MI. Treatment of hyperpigmentation. Facial Plast Surg Clin North Am. 2011 May;19(2):313-24. doi: 10.1016/j.fsc.2011.05.010. PubMed PMID: 21763992. 17: Durner J, Stojanovic M, Urcan E, Spahl W, Haertel U, Hickel R, Reichl FX. Effect of hydrogen peroxide on the three-dimensional polymer network in composites. Dent Mater. 2011 Jun;27(6):573-80. doi: 10.1016/j.dental.2011.02.013. Epub 2011 Mar 27. PubMed PMID: 21444108. 18: Yang ZD, Song ZW, Ren J, Yang MJ, Li S. Improved thin-layer chromatography bioautographic assay for the detection of actylcholinesterase inhibitors in plants. Phytochem Anal. 2011 Nov-Dec;22(6):509-15. doi: 10.1002/pca.1310. Epub 2011 Mar 24. 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