VU0071063 | CAS#333415-38-6 | Kir6.2/SUR1 activator

MedKoo Cat#: 563099 | Name: VU0071063

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

VU0071063 is an activator of Kir6.2/SUR1.

Chemical Structure

VU0071063

CAS#333415-38-6

Theoretical Analysis

MedKoo Cat#: 563099

Name: VU0071063

CAS#: 333415-38-6

Chemical Formula: C18H22N4O2

Exact Mass: 326.1743

Molecular Weight: 326.40

Elemental Analysis: C, 66.24; H, 6.79; N, 17.17; O, 9.80

Price and Availability

Size	Price	Availability
10mg	USD 250.00	2 Weeks
25mg	USD 490.00	2 Weeks
50mg	USD 750.00	2 Weeks

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Related CAS #

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Synonym

VU0071063; VU-0071063; VU 0071063;

IUPAC/Chemical Name

7-(4-(tert-Butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

InChi Key

ZFZAIHKQJBMYLO-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H22N4O2/c1-18(2,3)13-8-6-12(7-9-13)10-22-11-19-15-14(22)16(23)21(5)17(24)20(15)4/h6-9,11H,10H2,1-5H3

SMILES Code

O=C(N1C)N(C)C2=C(N(CC3=CC=C(C(C)(C)C)C=C3)C=N2)C1=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 326.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Raphemot R, Swale DR, Dadi PK, Jacobson DA, Cooper P, Wojtovich AP, Banerjee S, Nichols CG, Denton JS. Direct activation of β-cell KATP channels with a novel xanthine derivative. Mol Pharmacol. 2014 Jun;85(6):858-65. doi: 10.1124/mol.114.091884. Epub 2014 Mar 19. PubMed PMID: 24646456; PubMed Central PMCID: PMC4014665.